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Genetics of Late Life Involve Antagonistic Pleiotropy

Laurence D. Muller

in Does Aging Stop?

Published in print:
2011
Published Online:
September 2011
ISBN:
9780199754229
eISBN:
9780199896714
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199754229.003.0005
Subject:
Biology, Evolutionary Biology / Genetics

Reverse evolution experiments implicate antagonistic pleiotropy in the evolution of both mortality and fecundity during late life. Hybridization experiments do not implicate mutation accumulation in ... More


The quantitative genetics of senescence in wild animals

Anne Charmantier, Jon E. Brommer, and Daniel H. Nussey

in Quantitative Genetics in the Wild

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199674237
eISBN:
9780191779275
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199674237.003.0005
Subject:
Biology, Evolutionary Biology / Genetics, Ecology

There is now overwhelming empirical evidence for age-related declines in fitness-related traits, i.e. senescence, during adulthood in wild vertebrate populations, presumably underpinned by ... More


Life eternal in the face of senescence

Geoffrey E. Hill

in Mitonuclear Ecology

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198818250
eISBN:
9780191859465
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198818250.003.0006
Subject:
Biology, Ecology, Evolutionary Biology / Genetics

Unlike prokaryotes, eukaryotes are born, mature, grow old, and die. Why death is inevitable for all complex life is among the most important questions in evolutionary biology. The mitochondrial ... More


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