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Dealing with model uncertainty in reconstructing ancestral proteins in the laboratory: examples from archosaur visual pigments and coralfluorescent proteins

Belinda S.W. Chang, Mikhail V. Matz, Steven F. Field, Johannes Müller, and Ilke van Hazel

in Ancestral Sequence Reconstruction

Published in print:
2007
Published Online:
September 2008
ISBN:
9780199299188
eISBN:
9780191714979
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199299188.003.0015
Subject:
Biology, Evolutionary Biology / Genetics

This chapter discusses efficient experimental strategies to explore variation in ancestral sequence reconstructions. The experimental strategies are illustrated with two examples, ancestral ... More


Conclusion and a way forward

David A. Liberles

in Ancestral Sequence Reconstruction

Published in print:
2007
Published Online:
September 2008
ISBN:
9780199299188
eISBN:
9780191714979
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199299188.003.0020
Subject:
Biology, Evolutionary Biology / Genetics

This concluding chapter discusses the various issues raised in the course of the book and suggests a way forward for readers attempting ancestral sequence reconstruction. Ancestral sequence ... More


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