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Amyloid Imaging and (What is “Normal”?) Aging

William E. Klunk and Chester A. Mathis

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0014
Subject:
Neuroscience, Techniques, Development

One thing that has become clear from amyloid imaging studies is how early the full burden of plaques accumulate, often by the time a patient first develops symptoms. This finding brings with it the ... More


Structural Imaging of Mild Cognitive Impairment

Clifford R. Jack

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0012
Subject:
Neuroscience, Techniques, Development

This chapter describes the concept of mild cognitive impairment (MCI), the initial construct of amnestic MCI as well as the expanded construct that includes both amnestic and nonamnestic forms. The ... More


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