Michael H. Miller, Frank Sullivan, and John F. Dillon
- Published in print:
- 2013
- Published Online:
- May 2013
- ISBN:
- 9780199655786
- eISBN:
- 9780191757082
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/acprof:oso/9780199655786.003.0033
- Subject:
- Public Health and Epidemiology, Public Health, Epidemiology
Alcohol-related liver disease (ALD) represents a spectrum of liver damage caused by excessive alcohol consumption. The spectrum ranges from reversible fatty liver through to alcoholic hepatitis, ...
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Alcohol-related liver disease (ALD) represents a spectrum of liver damage caused by excessive alcohol consumption. The spectrum ranges from reversible fatty liver through to alcoholic hepatitis, alcohol-related cirrhosis, and hepatocellular carcinoma. The majority of heavy drinkers will not develop ALD despite apparently consuming similar amounts of alcohol in similar circumstances. The cause of this variation is probably multifactorial, and the combinations of factors differ between individuals, but accumulate to cross a threshold of response. This chapter discusses the mechanisms of alcohol-related liver damage and the clinical consequences this leads to.Less
Alcohol-related liver disease (ALD) represents a spectrum of liver damage caused by excessive alcohol consumption. The spectrum ranges from reversible fatty liver through to alcoholic hepatitis, alcohol-related cirrhosis, and hepatocellular carcinoma. The majority of heavy drinkers will not develop ALD despite apparently consuming similar amounts of alcohol in similar circumstances. The cause of this variation is probably multifactorial, and the combinations of factors differ between individuals, but accumulate to cross a threshold of response. This chapter discusses the mechanisms of alcohol-related liver damage and the clinical consequences this leads to.
Nigel Lane, Louise Powter, and Sam Patel (eds)
- Published in print:
- 2016
- Published Online:
- November 2020
- ISBN:
- 9780199680269
- eISBN:
- 9780191918360
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/oso/9780199680269.003.0006
- Subject:
- Clinical Medicine and Allied Health, Professional Development in Medicine
A 76-year-old woman was admitted to the acute medical unit with a one-week history of diarrhoea. She was opening her bowels four times per day. She had recently started a new medication.
On ...
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A 76-year-old woman was admitted to the acute medical unit with a one-week history of diarrhoea. She was opening her bowels four times per day. She had recently started a new medication.
On examination, her temperature was 36.4°C, pulse was 74 beats per minute, and blood pressure was 134/78 mmHg. She had a resting tremor in the right upper limb. Her abdomen was soft, with mild generalized tenderness.
Less
A 76-year-old woman was admitted to the acute medical unit with a one-week history of diarrhoea. She was opening her bowels four times per day. She had recently started a new medication.
On examination, her temperature was 36.4°C, pulse was 74 beats per minute, and blood pressure was 134/78 mmHg. She had a resting tremor in the right upper limb. Her abdomen was soft, with mild generalized tenderness.
