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T Cells: The Second Arm of Adapative Immunity

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0004
Subject:
Biology, Disease Ecology / Epidemiology

B cells and antibodies are only one arm of the adaptive immune system, specialized in removing foreign material from blood and lymph. The second arm of the adaptive system consists of T cells, which ... More


Immunomodulation in the Nervous and Vascular Systems During Inflammation and Autoimmunity: the Role of T Regulatory Cells

Kokona Chatzantoni and Athanasia Mouzaki

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0014
Subject:
Neuroscience, Molecular and Cellular Systems

The immune system is characterized by a complex network of cells and organs specialized to extinguish foreign invaders or malfunctioning cells of the organism. Although innate immunity, B-cell ... More


The Immune System and Cancer

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0011
Subject:
Biology, Disease Ecology / Epidemiology

Cancers arise as a result of mutations in genes controlling cell division. They may well arise in the body on a fairly frequent basis. Most or all cancers display information on their surface that ... More


Organ Transplantation

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0013
Subject:
Biology, Disease Ecology / Epidemiology

T cells are the major barrier to the transplantation of organs between other than genetically identical twins. The basis for immune rejection lies in the incredible heterogeneity among humans in ... More


The Immune Response to Infectious Disease: All Out War!

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0005
Subject:
Biology, Disease Ecology / Epidemiology

This chapter deals with the body's response to disease caused by infection with bacteria, viruses, or other microbes. The fundamental response is based on inflammation, which is mediated by the ... More


Immune responses in the central nervous system in inflammatory demyelinating disease

M. L. Cuzner and T. Smith

in Immune Responses in the Nervous System

Published in print:
1997
Published Online:
March 2012
ISBN:
9781872748795
eISBN:
9780191724381
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9781872748795.003.0006
Subject:
Neuroscience, Disorders of the Nervous System

Detailed immunocytochemical studies of the inflammatory lesion in post-mortem brain from acute cases of multiple sclerosis (MS) reinforce the growing conviction that the immune reaction can be ... More


Journey to the T cell

Jonathan C. Howard

in A Century of Nature: Twenty-One Discoveries that Changed Science and the World

Published in print:
2003
Published Online:
May 2013
ISBN:
9780226284132
eISBN:
9780226284163
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226284163.003.0014
Subject:
History, History of Science, Technology, and Medicine

Immunization against viral infection has saved countless lives, but how it works long remained a mystery. The discovery of antibodies at the end of the nineteenth century revealed one mechanism. ... More


The Non-Hodgkin Lymphomas

James R. Cerhan, Claire M. Vajdic, and John J. Spinelli

in Cancer Epidemiology and Prevention

Published in print:
2017
Published Online:
December 2017
ISBN:
9780190238667
eISBN:
9780190238698
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190238667.003.0040
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

The non-Hodgkin lymphomas (NHL) are a heterogeneous group of over forty lymphoid neoplasms that have undergone a major redefinition over the last twenty-five years, in part due to advances in ... More


Non-Hodgkin Lymphoma

Karin Ekström Smedby, Mads Melbye, and Hans-Olov Adami

in Textbook of Cancer Epidemiology

Published in print:
2018
Published Online:
February 2018
ISBN:
9780190676827
eISBN:
9780190676858
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190676827.003.0027
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

Non-Hodgkin lymphomas (NHL) are a heterogeneous group of malignancies originating from B- or T-lymphocytes and engaging lymphoid tissue. Clinically, NHL subtypes range from chronic indolent to ... More


The human immune responses to pertussis and pertussis vaccines

Françoise Mascart, Violette Dirix, and Camille Locht

in Pertussis: Epidemiology, Immunology, and Evolution

Published in print:
2018
Published Online:
February 2019
ISBN:
9780198811879
eISBN:
9780191850011
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198811879.003.0007
Subject:
Biology, Disease Ecology / Epidemiology, Evolutionary Biology / Genetics

Two types of pertussis vaccines are currently available: the first-generation, whole-cell (wP) and more recent, acellular (aP) vaccines. The aP vaccine has replaced the wP vaccine in most ... More


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