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The Immune Response to Infectious Disease: All Out War!

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0005
Subject:
Biology, Disease Ecology / Epidemiology

This chapter deals with the body's response to disease caused by infection with bacteria, viruses, or other microbes. The fundamental response is based on inflammation, which is mediated by the ... More


Extreme diversity in the major histocompatibility complex

Julian C. Knight

in Human Genetic Diversity: Functional Consequences for Health and Disease

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199227693
eISBN:
9780191711015
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199227693.003.0012
Subject:
Biology, Evolutionary Biology / Genetics, Disease Ecology / Epidemiology

The Major Histocompatibility Complex on chromosome 6 encodes a diverse array of genes involved in the immune and inflammatory response. The region is remarkably polymorphic and has been associated ... More


Functional significance of MHC variation in mate choice, reproductive outcome, and disease risk

Dagan A. Loisel, Susan C. Alberts, and Carole Ober

in Evolution in Health and Disease

Published in print:
2007
Published Online:
April 2010
ISBN:
9780199207466
eISBN:
9780191728167
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199207466.003.0008
Subject:
Biology, Evolutionary Biology / Genetics

This chapter surveys connections between the nervous system and the immune system, and suggests that their connections mediate many significant health outcomes. The nervous and immune systems are ... More


Female and Male Mate Choice: Similarities and Differences

Ingo Schlupp

in Male Choice, Female Competition, and Female Ornaments in Sexual Selection

Published in print:
2021
Published Online:
July 2021
ISBN:
9780198818946
eISBN:
9780191859892
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198818946.003.0002
Subject:
Biology, Animal Biology, Evolutionary Biology / Genetics

Females choose mating partners for three main reasons: direct benefits, indirect benefits, and compatibility, either genetic or social. In this chapter I am not trying to look at all angles of mate ... More


The Interaction of Antigens and Superantigens with the Human Class II Major Histocompatibility Complex Molecule HLA-DR1

T. Jardetzky

in Biological NMR Spectroscopy

Published in print:
1997
Published Online:
November 2020
ISBN:
9780195094688
eISBN:
9780197560754
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195094688.003.0022
Subject:
Chemistry, Organic Chemistry

The initiation and maintenance of an immune response to pathogens requires the interactions of cells and proteins that together are able to distinguish appropriate non-self targets from the ... More


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