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Beginning of an Era: The First Blockbuster Drug, Tagamet

Jie Jack Li

in Title Pages

Published in print:
2014
Published Online:
November 2020
ISBN:
9780199737680
eISBN:
9780197563014
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199737680.003.0005
Subject:
Chemistry, Medicinal Chemistry

Tagamet emerged as the first blockbuster drug when its sales exceeded $1 billion in 1986, three years after its introduction to the market. An anti–peptic ulcer drug, ... More


More Blockbuster Drugs for Ulcers: Prilosec, Nexium, and Other Proton-Pump Inhibitors

Jie Jack Li

in Blockbuster Drugs: The Rise and Fall of the Pharmaceutical Industry

Published in print:
2014
Published Online:
November 2020
ISBN:
9780199737680
eISBN:
9780197563014
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199737680.003.0006
Subject:
Chemistry, Medicinal Chemistry

In the first half of the 19th century, British physician William Prout conclusively showed that gastric juice contains hydrochloric acid. U.S. Army officer William ... More


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