Jump to ContentJump to Main Navigation

You are looking at 1-10 of 10 items

  • Keywords: GWAS x
Clear All Modify Search

View:

Genome-Wide Association Studies: Back to the Future

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0007
Subject:
Anthropology, Social and Cultural Anthropology

This chapter examines findings from the newly developed technology of genome-wide association studies (GWAS) being applied to the investigation of Alzheimer disease (AD), primarily in the United ... More


Theranostics and Translation toward Personalized Medicine for Multiple Sclerosis

Ariel Miller, Tamar Paperna, Opher Caspi, Izabella Lejbkowicz, Elsebeth Staun-Ram, and Nili Avidan

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0011
Subject:
Neuroscience, Disorders of the Nervous System

Recently, medicine began moving to more informed healthcare management and medical treatment guided by diagnostics, termed, theranostics. In the last decade, the search for markers for disease ... More


Genetic Epidemiology of Cancer

Christopher Haiman and David Hunter

in Textbook of Cancer Epidemiology

Published in print:
2008
Published Online:
September 2009
ISBN:
9780195311174
eISBN:
9780199865093
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195311174.003.0004
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Clarifying the complex etiologic role of environmental and genetic factors in carcinogenesis will be challenging but necessary to understand fully the causes of cancer and how it can be prevented. ... More


Nurture via Nature: Genetics, Environment, and Cognition

Pamela M. Greenwood and Raja Parasuraman

in Nurturing the Older Brain and Mind

Published in print:
2012
Published Online:
August 2013
ISBN:
9780262017145
eISBN:
9780262301336
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262017145.003.0012
Subject:
Psychology, Cognitive Psychology

This chapter focuses on the effects of genetic modulation on cognitive aging. The use of molecular genetics for understanding cognition genetics is discussed along with the advantages of molecular ... More


Therapeutic Translation of Genomic Science: Opportunities and Limitations of GWAS

Manuel Hermosilla and Jorge Lemus

in Economic Dimensions of Personalized and Precision Medicine

Published in print:
2019
Published Online:
September 2019
ISBN:
9780226611068
eISBN:
9780226611235
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226611235.003.0003
Subject:
Economics and Finance, Microeconomics

Many scientists predicted a swift revolution in human therapeutics after the completion of the Human Genome Project (“HGP”). This revolution, however, has been slow to materialize in spite of the ... More


The genetics of personality/psychopathology: A brief review of constructs, results, approaches, and implications

Thomas J Bouchard, Wendy Johnson, and Irving I Gottesman

in Genes, brain, and emotions: Interdisciplinary and Translational Perspectives

Published in print:
2019
Published Online:
June 2019
ISBN:
9780198793014
eISBN:
9780191834745
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198793014.003.0019
Subject:
Neuroscience, Development, Disorders of the Nervous System

The chapter argues that the best evidence supports the contention that psychiatric “conditions” are not discrete “disorders” but rather dimensional and part of the personality sphere. The personality ... More


Genetics of Psychological Well-Being: The role of heritability and genetics in positive psychology

Michael Pluess (ed.)

Published in print:
2015
Published Online:
August 2015
ISBN:
9780199686674
eISBN:
9780191766787
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199686674.001.0001
Subject:
Psychology, Cognitive Psychology, Evolutionary Psychology

The science of psychological well-being has gained a lot of interest in the last decade. While it has been shown that psychological well-being is partly heritable, research focused on the ... More


Multilocus evolution

Glenn-Peter Sætre and Mark Ravinet

in Evolutionary Genetics: Concepts, Analysis, and Practice

Published in print:
2019
Published Online:
July 2019
ISBN:
9780198830917
eISBN:
9780191868993
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830917.003.0006
Subject:
Biology, Evolutionary Biology / Genetics, Biomathematics / Statistics and Data Analysis / Complexity Studies

Most phenotypic traits are affected by a multitude of genes, which may interact in complex ways. This means that the single locus model explored in chapters 3 and 4 is not always able to capture the ... More


The Neutral Divergence of Quantitative Traits

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0012
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

The joint action of genetic drift and mutation results in the divergence of trait means over time. This chapter examines the expected amount of divergence, which forms the basis for a number of tests ... More


Schizophrenia Genetics: Experimental and Theoretical Approaches

Kenneth F. Schaffner

in Behaving: What's Genetic, What's Not, and Why Should We Care?

Published in print:
2016
Published Online:
May 2016
ISBN:
9780195171402
eISBN:
9780190464103
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195171402.003.0008
Subject:
Philosophy, Philosophy of Science, Moral Philosophy

This chapter on schizophrenia genetics examines the experimental basis of searches for schizophrenia genes, new ways to think about them, and some preliminary results of the post-2005 genome-wide ... More


View: