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Common Mechanisms of Bacterial Metal Homeostasis

James A. Imlay

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0005
Subject:
Public Health and Epidemiology, Public Health

Transition metals are required for the function of nearly half the enzymatic machinery of organisms. Metals compete for enzyme-binding sites and inappropriate metallation inhibits enzyme function. ... More


Escherichia coli

Rowland H. Davis

in The Microbial Models of Molecular Biology: From Genes to Genomes

Published in print:
2003
Published Online:
April 2010
ISBN:
9780195154368
eISBN:
9780199893935
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195154368.003.0007
Subject:
Biology, Biochemistry / Molecular Biology

This chapter focuses on the choice of a model organism, in this case the bacterium Escherichia coli, in the development of molecular genetics. It shows that this choice was made inconspicuously just ... More


Gene-regulatory networks: from DNA to metabolites and back

Baltazar D. Aguda and Avner Friedman

in Models of Cellular Regulation

Published in print:
2008
Published Online:
September 2008
ISBN:
9780198570912
eISBN:
9780191718717
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570912.003.0004
Subject:
Physics, Soft Matter / Biological Physics

DNA has at least three functions essential to life: (i) its chemistry provides a mechanism for replicating genes (via the Watson–Crick base pairing); (ii) in its long strands are nucleotide sequences ... More


Control of DNA replication in a prokaryote

Baltazar D. Aguda and Avner Friedman

in Models of Cellular Regulation

Published in print:
2008
Published Online:
September 2008
ISBN:
9780198570912
eISBN:
9780191718717
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570912.003.0005
Subject:
Physics, Soft Matter / Biological Physics

A cell-division cycle, or cell cycle, is a combination of growth to double the amounts of cellular components, and division of these components between two daughter cells. This chapter discusses the ... More


Technical Changes: Technology and Industry

A. D. Cliff, M.R. Smallman-Raynor, P. Haggett, D.F. Stroup, and S.B. Thacker

in Infectious Diseases: A Geographical Analysis: Emergence and Re-emergence

Published in print:
2009
Published Online:
November 2020
ISBN:
9780199244737
eISBN:
9780191917509
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199244737.003.0015
Subject:
Earth Sciences and Geography, Social and Political Geography

In this chapter, we examine the second of the five overlapping drivers of disease emergence and re-emergence shown in Figure II.1 “technology and industry. Technological developments have yielded ... More


Experimental Evolution from the Bottom Up

Daniel E. Dykhuizen and Anthony M. Dean

in Experimental Evolution: Concepts, Methods, and Applications of Selection Experiments

Published in print:
2009
Published Online:
March 2012
ISBN:
9780520247666
eISBN:
9780520944473
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520247666.003.0004
Subject:
Biology, Evolutionary Biology / Genetics

This chapter focuses on the bottom-up approach used to understand the nature of natural selection, and begins by discussing a bottom-up analysis of the lactose system. The study of lactose metabolism ... More


Pressure- and Temperature-Induced Inactivation of Microorganisms

Horst Ludwig and Wilhelm Scigalla

in High Pressure Effects in Molecular Biophysics and Enzymology

Published in print:
1996
Published Online:
November 2020
ISBN:
9780195097221
eISBN:
9780197560839
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195097221.003.0025
Subject:
Chemistry, Organic Chemistry

Bacteria are unstable when the temperature or pressure is sufficiently high. Their inactivation by pressure is the result of a complicated interplay of both temperature and pressure effects. The ... More


Larval Subjects, Autonomous Systems and E. Coli Chemotaxis

John Protevi

in Deleuze and the Body

Published in print:
2011
Published Online:
March 2012
ISBN:
9780748638642
eISBN:
9780748652679
Item type:
chapter
Publisher:
Edinburgh University Press
DOI:
10.3366/edinburgh/9780748638642.003.0002
Subject:
Philosophy, General

This chapter examines the relation between autopoietic theory and Gilles Deleuze's thought. It addresses Deleuze's claim in the second chapter of his Difference and Repetition that there are ... More


One Discovery, Three Stories

Frederic Lawrence Holmes

in Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology"

Published in print:
2001
Published Online:
October 2013
ISBN:
9780300085402
eISBN:
9780300129663
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300085402.003.0010
Subject:
History, History of Science, Technology, and Medicine

This chapter discusses Meselson's and Stahl's decision to switch from 5-BU to 15N to produce heavy DNA and, at the same time, to carry out the transfer experiments with bacteria in place of phage. ... More


The Geographical Matrix

A. D. Cliff, M.R. Smallman-Raynor, P. Haggett, D.F. Stroup, and S.B. Thacker

in Infectious Diseases: A Geographical Analysis: Emergence and Re-emergence

Published in print:
2009
Published Online:
November 2020
ISBN:
9780199244737
eISBN:
9780191917509
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199244737.003.0013
Subject:
Earth Sciences and Geography, Social and Political Geography

A historical–geographical exploration of disease emergence is confronted by a series of fundamental questions: Which diseases have emerged? When? And where? For some high-profile diseases, such as ... More


Synthetic Gene Regulatory Systems

Mads Kærn and Ron Weiss

in System Modeling in Cellular Biology: From Concepts to Nuts and Bolts

Published in print:
2006
Published Online:
August 2013
ISBN:
9780262195485
eISBN:
9780262257060
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262195485.003.0013
Subject:
Mathematics, Mathematical Biology

This chapter focuses on the mathematical design and experimental implementation of selected synthetic gene regulatory networks that embody important architectural properties. The chapter is organized ... More


Dictyostelium, the Amoeba and the Slug

Pete A. Ensminger

in Life Under the Sun

Published in print:
2001
Published Online:
October 2013
ISBN:
9780300088045
eISBN:
9780300133523
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300088045.003.0011
Subject:
Environmental Science, Climate

This chapter reveals the discovery and different stages in the life cycle of Dictyostelium discoideum, the role of cAMP in intercellular communication, and the porphyrin photoreceptor in Escherichia ... More


Exploring Structural, Functional, and Kinetic Aspects of Nucleic Acid–Protein Complexes with Pressure: Nucleosomes and RNA Polymerase

Mauro Villas-Boas and Ana Sepulveda De Rezende

in High Pressure Effects in Molecular Biophysics and Enzymology

Published in print:
1996
Published Online:
November 2020
ISBN:
9780195097221
eISBN:
9780197560839
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195097221.003.0012
Subject:
Chemistry, Organic Chemistry

High pressure has provided us with new insights into two complex DNA-protein systems: nucleosomes and RNA polymerase. In spite of their complexity, we can derive new and useful information about ... More


Control Strategies in Times of Adversity: How Organisms Survive Stressful Conditions

Hana El-Samad

in Control Theory and Systems Biology

Published in print:
2009
Published Online:
August 2013
ISBN:
9780262013345
eISBN:
9780262258906
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013345.003.0005
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

This chapter analyzes the bacterial heat-shock response as a modular controller. It specifically describes the salient organizational properties and design principles of the system in Escherichia ... More


Kinetics in Spatially Extended Systems

Karsten Kruse and Johan Elf

in System Modeling in Cellular Biology: From Concepts to Nuts and Bolts

Published in print:
2006
Published Online:
August 2013
ISBN:
9780262195485
eISBN:
9780262257060
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262195485.003.0009
Subject:
Mathematics, Mathematical Biology

This chapter presents theoretical approaches for describing the dynamics of biological systems. The first part discusses continuum descriptions in terms of partial differential equations. Such a ... More


Methods to Identify Cellular Architecture and Dynamics from Experimental Data

Rudiyanto Gunawan, Kapil G. Gadkar, and Francis J. Doyle

in System Modeling in Cellular Biology: From Concepts to Nuts and Bolts

Published in print:
2006
Published Online:
August 2013
ISBN:
9780262195485
eISBN:
9780262257060
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262195485.003.0011
Subject:
Mathematics, Mathematical Biology

This chapter highlights the methodologies and challenges in the reverse engineering of cellular networks, in particular the identification of network dynamics using engineering approaches. The ... More


The Microbe Solution

Sharon Levy

in The Marsh Builders: The Fight for Clean Water, Wetlands, and Wildlife

Published in print:
2018
Published Online:
November 2020
ISBN:
9780190246402
eISBN:
9780197559550
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190246402.003.0007
Subject:
Environmental Science, Pollution and Threats to the Environment

In the hot, dry summer of 1858, the Thames was a stew of sewage that festered in the sun, giving off an unbearable stench. “We believe this to be the uncleanest, foulest river in the known world,” ... More


Environmental Changes: Ecological Modifications

A. D. Cliff, M.R. Smallman-Raynor, P. Haggett, D.F. Stroup, and S.B. Thacker

in Infectious Diseases: A Geographical Analysis: Emergence and Re-emergence

Published in print:
2009
Published Online:
November 2020
ISBN:
9780199244737
eISBN:
9780191917509
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199244737.003.0017
Subject:
Earth Sciences and Geography, Social and Political Geography

Diseases originate, spread, and persist or wither, within a specific environmental context. For the entire time during which humans have lived on the earth, this environmental context has changed ... More


Spatial Detection of (Re-)emerging Diseases

A. D. Cliff, M.R. Smallman-Raynor, P. Haggett, D.F. Stroup, and S.B. Thacker

in Infectious Diseases: A Geographical Analysis: Emergence and Re-emergence

Published in print:
2009
Published Online:
November 2020
ISBN:
9780199244737
eISBN:
9780191917509
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780199244737.003.0021
Subject:
Earth Sciences and Geography, Social and Political Geography

The development of models and surveillance systems to give early warning of a new or re-emerging disease is an important first step in devising control strategies to protect the public health. In ... More


High-Pressure FTIR Studies of the Secondary Structure of Proteins

Yoshihiro Taniguchi and Naohiro Takeda

in High Pressure Effects in Molecular Biophysics and Enzymology

Published in print:
1996
Published Online:
November 2020
ISBN:
9780195097221
eISBN:
9780197560839
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195097221.003.0010
Subject:
Chemistry, Organic Chemistry

Infrared spectra of five globular proteins (bovine pancreas ribonuclease A, horse skeletal muscle myoglobin, bovine pancreas insulin, horse heart cytochrome c, egg white lysozyme) in 5% D2O ... More


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