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Engineering Human Nature in the Genome Age: A Long View

Nathaniel Comfort

in Nature Remade: Engineering Life, Envisioning Worlds

Published in print:
2021
Published Online:
January 2022
ISBN:
9780226783260
eISBN:
9780226783574
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226783574.003.0012
Subject:
Biology, Evolutionary Biology / Genetics

All attempts to engineer human biology ride high on promises: They will enable us to predict disease, prevent crime, make our innate nature legible, take control of our own evolution. Here I sketch ... More


Science Between Myth and History: The Quest for Common Ground and Its Importance for Scientific Practice

José G. Perillán

Published in print:
2021
Published Online:
July 2021
ISBN:
9780198864967
eISBN:
9780191897399
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198864967.001.0001
Subject:
Physics, History of Physics

Scientists regularly employ historical narrative as a rhetorical tool in their communication of science, yet there’s been little reflection on its effects within scientific communities and beyond. ... More


Human Flourishing in an Age of Gene Editing

Erik Parens and Josephine Johnston (eds)

Published in print:
2019
Published Online:
August 2019
ISBN:
9780190940362
eISBN:
9780190940379
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190940362.001.0001
Subject:
Philosophy, Moral Philosophy

The potential use of CRISPR-Cas9 and other new gene editing technologies to alter the DNA of human beings raises a host of questions. Some questions are about safety: Can these technologies be ... More


Cloning Animals, Cells, and Genes: Where Did Cloning Come From, and Where Is It Going To Right Now?

Scott Gilbert

in Fear, Wonder, and Science in the New Age of Reproductive Biotechnology

Published in print:
2017
Published Online:
January 2019
ISBN:
9780231170949
eISBN:
9780231544580
Item type:
chapter
Publisher:
Columbia University Press
DOI:
10.7312/columbia/9780231170949.003.0007
Subject:
Biology, Bioethics

Every technology has its history, and this chapter looks at the technologies of animal cloning and how they changed when it became apparent that one could perform some of the medical task of cloning ... More


Six Questions on the Special, the Inclusive, and the Universal

Rachel Adams

in Unexpected: Parenting, Prenatal Testing, and Down Syndrome

Published in print:
2021
Published Online:
September 2021
ISBN:
9781479816637
eISBN:
9781479827183
Item type:
chapter
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479816637.003.0006
Subject:
Sociology, Marriage and the Family

Rachel Adams uses a question-and-answer format to extend the conversations she has had with her friend and colleague Alison Piepmeier and to imagine which issues Alison might have tackled, had her ... More


“Feed the Green”

Jane Caputi

in Call Your "Mutha": A Deliberately Dirty-Minded Manifesto for the Earth Mother in the Anthropocene

Published in print:
2020
Published Online:
July 2020
ISBN:
9780190902704
eISBN:
9780190902742
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190902704.003.0007
Subject:
Political Science, American Politics, Political Theory

This dream-inspired chapter seeks the spiritual meanings of green, the color announcing the living presence of nature. Multitudinous green beings appear in sacred, artistic, and popular traditions, ... More


Introduction: The Gene Revolution

John Parrington

in Redesigning Life: How genome editing will transform the world

Published in print:
2020
Published Online:
December 2020
ISBN:
9780198766834
eISBN:
9780191918957
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198766834.003.0001
Subject:
Biology, Evolutionary Biology / Genetics

We are in the middle of a scientific revolution in the biological sciences. In the 1970s scientists discovered ways to cut and paste DNA in a test tube, and then introduce gene ‘constructs’ into ... More


The Gene Scissors

John Parrington

in Redesigning Life: How genome editing will transform the world

Published in print:
2020
Published Online:
December 2020
ISBN:
9780198766834
eISBN:
9780191918957
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198766834.003.0005
Subject:
Biology, Evolutionary Biology / Genetics

We are currently in the middle of a revolution in the biological sciences. The genome project made it possible to read the sequence of individual genomes, but what was lacking until recently was a ... More


CRISPR—a challenge for national and international regulation

Dianne Nicol

in Can precision medicine be personal; Can personalized medicine be precise?

Published in print:
2022
Published Online:
April 2022
ISBN:
9780198863465
eISBN:
9780191895913
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198863465.003.0014
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The law and other forms of regulation are important tools in ensuring that the benefits of precision medicines are enjoyed by all society, and that scientific risks and ethical and social concerns ... More


The CRISPR Era, the National Academies Report, and the Median Trait Barrier

John H. Evans

in The Human Gene Editing Debate

Published in print:
2020
Published Online:
January 2021
ISBN:
9780197519561
eISBN:
9780197519592
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780197519561.003.0003
Subject:
Sociology, Social Movements and Social Change, Health, Illness, and Medicine

This chapter begins with the discovery of human gene editing, and how the immediate ethical response used the existing weakened barriers. The chapter then turns to a detailed analysis of how an ... More


Disruptive Technologies

David Segal

in Materials for the 21st Century

Published in print:
2017
Published Online:
July 2017
ISBN:
9780198804079
eISBN:
9780191842320
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198804079.003.0009
Subject:
Physics, Condensed Matter Physics / Materials, Soft Matter / Biological Physics

Chapter 9 describes potential disruptive technologies in the 21st century. It covers the expanding area of gene editing, also known as genome editing or CRISPR. It describes ‘wonder materials’ such ... More


Facts, Alternative Facts and Patent Literature

David Segal

in One Hundred Patents That Shaped the Modern World

Published in print:
2018
Published Online:
April 2019
ISBN:
9780198834311
eISBN:
9780191872426
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198834311.003.0001
Subject:
Physics, History of Physics, Condensed Matter Physics / Materials

The mathematician Kurt Gödel showed in his Incompleteness Theorem in the early 1930s that there are some statements in mathematics that are true but cannot be proven. Whether statements are true is ... More


Mutational mechanisms and evolvability

Arlin Stoltzfus

in Mutation, Randomness, and Evolution

Published in print:
2021
Published Online:
May 2021
ISBN:
9780198844457
eISBN:
9780191880063
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198844457.003.0005
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Well-studied cases of programmed DNA rearrangements, e.g., somatic recombination in the emergence of specific antibodies, suggest a rubric for specially evolved mutation systems: they amplify the ... More


New Technologies, New Issues: Gene Drivers and Geoengineering

Charles Weiss

in The Survival Nexus: Science, Technology, and World Affairs

Published in print:
2021
Published Online:
October 2021
ISBN:
9780190946265
eISBN:
9780197571941
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190946265.003.0014
Subject:
Physics, History of Physics

Gene drivers and geoengineering promise great benefits but involve large risks. Yet, no norms govern their use. Both have global effects but could be implemented by governments, private firms, or ... More


Genetic Engineering, GMOs, and Genome Editing

Alan McHughen

in DNA Demystified: Unravelling the Double Helix

Published in print:
2020
Published Online:
July 2020
ISBN:
9780190092962
eISBN:
9780190092993
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190092962.003.0011
Subject:
Biology, Bioethics

DNA is the very core of human existence. The thought of humans manipulating the DNA base sequence of a living thing can be unsettling, disturbing, and sometimes intensely controversial. What are some ... More


Myth-Historical CRISPR Edits: Modifying Futures by Controlling Pasts

José G. Perillán

in Science Between Myth and History: The Quest for Common Ground and Its Importance for Scientific Practice

Published in print:
2021
Published Online:
July 2021
ISBN:
9780198864967
eISBN:
9780191897399
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198864967.003.0004
Subject:
Physics, History of Physics

History is not always written by the victors. Competing histories often become ssbattlegrounds for those who want to declare themselves victors. Emerging from the frontiers of molecular biology, ... More


Sequencing the genome and beyond

Glenn-Peter Sætre and Mark Ravinet

in Evolutionary Genetics: Concepts, Analysis, and Practice

Published in print:
2019
Published Online:
July 2019
ISBN:
9780198830917
eISBN:
9780191868993
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830917.003.0010
Subject:
Biology, Evolutionary Biology / Genetics, Biomathematics / Statistics and Data Analysis / Complexity Studies

Science is defined by continual progress and new technologies. This final chapter starts with introducing what it means to sequence and assemble a reference genome. It is easy to forget that the true ... More


Optimizing Cognitive PerformanceGenetic and Epigenetic Techniques

Valerie E. Martindale

in Human Performance Optimization: The Science and Ethics of Enhancing Human Capabilities

Published in print:
2019
Published Online:
January 2019
ISBN:
9780190455132
eISBN:
9780190455156
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190455132.003.0013
Subject:
Psychology, Cognitive Psychology, Cognitive Neuroscience

Optimizing human cognitive performance by genetic and epigenetic means requires consideration of the goal and context of the desired cognitive performance. This chapter considers two examples to ... More


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