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Every technology has its history, and this chapter looks at the technologies of animal cloning and how they changed when it became apparent that one could perform some of the medical task of cloning with embryonic stem cells. These stem cells were difficult to obtain (and morally worrisome to many) and a new technology, induced pluripotential stem cells, enabled researchers to transform nearly any cell of the body into an embryonic stem cell. This has brought new worries concerning the ability to manipulate these cells to enhance a person’s capabilities.

Chapter 9 describes potential disruptive technologies in the 21st century. It covers the expanding area of gene editing, also known as genome editing or CRISPR. It describes ‘wonder materials’ such as graphene and high-temperature superconductors. Three-dimensional printing, also known as 3D printing, is covered in the text. Two materials that have intriguing properties, namely metamaterials and auxetic materials and their properties, are described.

The mathematician Kurt Gödel showed in his Incompleteness Theorem in the early 1930s that there are some statements in mathematics that are true but cannot be proven. Whether statements are true is important in the twenty-first century, an age of ‘fake news’ and alternative facts. Patent documents are true and accurate as they are examined and can be challenged for accuracy. This chapter outlines the patenting procedure. It also highlights the role of patents as a source of information alongside other sources. Accurate and true information is important for people with interests in engineering, physical sciences and life sciences. Patent infringement and patent trolls (non-practicing entities) are described. The following technical areas are grouped together to describe how they developed over time and how they may develop in the twenty-first century: communications, computing including quantum computing, life sciences including gene editing (CRISPR), transport and unexpected consequences of technological change.

Science is defined by continual progress and new technologies. This final chapter starts with introducing what it means to sequence and assemble a reference genome. It is easy to forget that the true genome is not linear but has structure and function. In this chapter the genome is explored as a 3D entity—from how it is transcribed, to how proteins interact with it, and finally to how it is actually structured. This also gives an opportunity to focus on epigenetics and how to interpret processes such as DNA methylation in an evolutionary context. The second part of the chapter focuses on ways we can interact with the genome—exploring how we might test the function and role that candidate genes play. The chapter introduces transgenics, in particular the transformative technology of CRISPR/CAS9, and explores how this might change the face of evolutionary biology in the near future.

Optimizing human cognitive performance by genetic and epigenetic means requires consideration of the goal and context of the desired cognitive performance. This chapter considers two examples to illustrate how optimization will depend on deciding what qualities are desired, defining such traits or phenotypes, and then considering the environment in which genes are expressed. The warrior/worrier gene provides a way to explore the alteration of a single gene with simple dominance. The most commonly desired genetic cognitive trait, intelligence, is considered as an example of a multigenic trait. The genetic techniques for optimization of human cognition are described using plasmid introduction, direct gene editing, and genetic alteration of the microbiome. The approval of three medical genetic therapies in 2017 indicates a high probability that genetic enhancement will become possible in less than 20 years.