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Physical Activity, Fitness, and Delayed Mortality

Michael J. Lamonte and Steven N. Blair

in Epidemiologic Methods in Physical Activity Studies

Published in print:
2008
Published Online:
September 2009
ISBN:
9780195183009
eISBN:
9780199865116
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195183009.003.0008
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

A large amount of evidence from observational studies indicates that low levels of physical activity and cardiorespiratory fitness (CRF) are associated with increased mortality risk. This chapter ... More


The CRF Signal: Uncovering an Information Molecule

Jay Schulkin

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.001.0001
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

This book discusses just how diverse a peptide corticotrophin-releasing factor (CRF) is, as demonstrated by its presence in various tissues in the body, including the skin, the placenta, and various ... More


Anxiety Reduction and Maternal Aggression in Postpartum Nonhuman Mammals

Michael Numan

in The Parental Brain: Mechanisms, Development, and Evolution

Published in print:
2020
Published Online:
July 2020
ISBN:
9780190848675
eISBN:
9780190848705
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190848675.003.0006
Subject:
Neuroscience, Development

Chapter 6 explores the neural mechanisms that regulate the decrease in anxiety and increase in maternal aggression that co-occur in postpartum mammals. Too much anxiety antagonizes maternal ... More


Cancer fatigue

Ravi Bhargava and Martin Chasen

in Palliative Medicine: A Case-Based Manual

Published in print:
2021
Published Online:
January 2022
ISBN:
9780198837008
eISBN:
9780191873874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198837008.003.0011
Subject:
Palliative Care, Palliative Medicine and Older People

The chapter focuses on the assessment and management of the multidimensional components, while discussing the role of exercise and its impact on the physical, emotional, and psychosocial state of ... More


Introduction

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0001
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

CRF is well known and studied as a hypothalamic-releasing factor. It, along with ACTH and cortisol, are mobilized under diverse conditions, including adversity, and are often thought of as part of ... More


Evolution and Diversification of Function of an Information Molecule: Corticotrophin-Releasing Factor

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0002
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

Chapter 2 begins with a depiction of the evolutionary origins of CRF in living things. CRF appears to date back hundreds of millions of years. It is found in diverse invertebrates, including flies ... More


Conservation of CRF in Brains and its Regulation by Adrenal Steroids

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0003
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

The regulation of the HPA axis has been categorized as the classical mechanism of slow-acting genomic regulation of gene products, but this has given way to both slow and fast regulation of the HPA ... More


Radical Change: Metamorphosis and Parturition

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

Chapter 4 talks about how CRF is involved in two quite striking processes: metamorphosis and parturition. Both of these processes revolve around the wondrously vital feature of radical change. In ... More


CRF: Contributor to Fear and Anxiety

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0005
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

Chapter 5 explains how excessive fear is tied to anxiety disorders, and vulnerability to the breakdown of mental and physical health. CRF in the brain is tied to these events. CRF, for instance, may ... More


Social Contact, Gonadal Steroids, and CRF

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

Chapter 6 begins with a brief discussion of CRF in approach/avoidance behaviors across pre- and postnatal events. What will follow is the description of diverse steroids, in particular gonadal ... More


Cravings and Addictions: The Contributions of CRF to Approach, Ingestion, and Withdrawal

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0008
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

The allure of afflictions and appetites gone awry are endless in the modern era. They range from the endless junk food we eat, to the computer games that lock our children to distraction, compulsion, ... More


Conclusion: The Study of CRF—An Epistemic and Medical Endeavor

Jay Schulkin

in The CRF Signal: Uncovering an Information Molecule

Published in print:
2017
Published Online:
June 2017
ISBN:
9780198793694
eISBN:
9780191835506
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198793694.003.0009
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

Chapter 9 addresses what constitutes an information molecule, in general, and CRF, in particular. Our age is the age of information and CRF is now set in the larger context of the information age of ... More


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