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Control of inflammation

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0010
Subject:
Neuroscience, Techniques

While inflammatory diseases affecting the CNS can produce a huge range of symptoms, depending on the exact nature of the disease process, the range of therapeutic options in these conditions is ... More


Clinical aspects of traumatic injury to central nervous system axons

MILAN R. DIMITRIJEVIC

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0034
Subject:
Neuroscience, Disorders of the Nervous System

This chapter begins by describing the features of segmental reflex activities in patients with chronic and clinically complete spinal cord injury. It then presents evidence that some of those ... More


Axonal Regeneration in the Central Nervous System of Mammals

Isabel Klusman and Martin E. Schwab

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0037
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter discusses axonal regeneration in the adult mammalian central nervous system (CNS). In contrast to the situation in the peripheral nervous system (PNS), where injured axons often ... More


Reaction of Glial Cells in Infectious Disorders of the Central Nervous System

Martina Deckert and Dirk Schlüter

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0047
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter shows the disease-specific, individual, and finely tuned reaction pattern of astrocytes and microglia during central nervous system (CNS) infections and their contribution to the ... More


Leslie L. Iversen

Larry R. Squire

in The History of Neuroscience in Autobiography Volume 6

Published in print:
2009
Published Online:
May 2009
ISBN:
9780195380101
eISBN:
9780199864362
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195380101.003.0006
Subject:
Neuroscience, History of Neuroscience

This chapter presents an autobiography of Leslie L. Iversen. Iversen has been at the forefront of research on neurotransmitters and neuropeptides and understanding the mode of action of CNS drugs. He ... More


Axon regeneration in the CNS

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0022
Subject:
Neuroscience, Techniques

This chapter describes the efforts that have been made to date to persuade axons in the CNS to regrow, and the resulting re-innervation of terminal structures and behavioural recovery. The success or ... More


Central nervous system tumours

Peter Hoskin and Wendy Makin

in Oncology for Palliative Medicine

Published in print:
2003
Published Online:
November 2011
ISBN:
9780192628114
eISBN:
9780191730115
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192628114.003.0014
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter discusses the central nervous system (CNS) and the malignant tumours prevalent in this region of the body. Primary tumours of the central nervous system are rare, but they are more ... More


Microglia in the developing and mature central nervous system

V. Hugh Perry

in Glial Cell Development: basic principles and clinical relevance

Published in print:
1997
Published Online:
March 2012
ISBN:
9781872748542
eISBN:
9780191724367
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9781872748542.003.0007
Subject:
Neuroscience, Development

This chapter shows that macrophages play a part in the removal of cellular debris from the developing central nervous system (CNS) and then differentiate to become microglia, the resident macrophages ... More


Why have dendrites?: A computational perspective

Bartlett W. Mel

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0016
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter is concerned with how dendritic trees may contribute to the information-processing functions of individual nerve cells in the CNS. After reviewing the history of ideas about dendritic ... More


Metabolic damage

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0003
Subject:
Neuroscience, Techniques

Many conditions can cause metabolic damage to the CNS, and they do so through a variety of mechanisms. Stroke, for instance, causes anoxic damage to a region of the brain, the actual cell death being ... More


Inflammation and demyelination: With Neil Scolding

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0004
Subject:
Neuroscience, Techniques

Although the CNS has conventionally been viewed as an immunologically privileged site, the importance of immunological responses in the pathogenesis of CNS disease has become increasingly apparent ... More


Concluding discussion

Risto Näätänen, Teija Kujala, and Gregory Light

in The Mismatch Negativity: A Window to the Brain

Published in print:
2019
Published Online:
May 2019
ISBN:
9780198705079
eISBN:
9780191874192
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198705079.003.0008
Subject:
Neuroscience, Sensory and Motor Systems

This chapter looks at potential common underlying factors linking MMN/MMNm deficiency to the broad range of heterogeneous clinical conditions outlined in the book. Several promising clinical ... More


The messenger is not the message; or is it?

Barry A. Trimmer

in Beyond Neurotransmission: Neuromodulation and its Importance for Information Processing

Published in print:
1999
Published Online:
March 2012
ISBN:
9780198524243
eISBN:
9780191724435
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198524243.003.0002
Subject:
Neuroscience, Behavioral Neuroscience

This chapter begins by describing neural coding systems (the ‘messages’) thought to take part in information processing in the brain. It then discusses the possible roles played by neurotransmitters ... More


Failure of CNS regeneration

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0012
Subject:
Neuroscience, Techniques

Axons in the mammalian peripheral nervous system (PNS) regenerate well. Axons in the adult mammalian central nervous system (CNS), however, do not spontaneously regenerate, with the result that any ... More


Anatomical plasticity

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0013
Subject:
Neuroscience, Techniques

In mammals, after damage to major axon tracts or large areas of neuronal tissue, there is permanent loss of function. Axons will not regenerate, and killed neurones are not replaced. This is in ... More


Management of Primary Brain Tumours

Neil G. Burnet, V. Ramesh Bulusu, and Sarah J. Jefferies

in Palliative Care Consultations in Primary and Metastatic Brain Tumours

Published in print:
2004
Published Online:
November 2011
ISBN:
9780198528074
eISBN:
9780191730382
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198528074.003.0001
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

Neuro-oncology is the most difficult area for patients, family, and staff. Of all cancers, gliomas are one of the most devastating cancers, and which posit unique problems and challenges. Primary ... More


Neural Dynamics

Gregor Schöner, Hendrik Reimann, and Jonas Lins

in Dynamic Thinking: A Primer on Dynamic Field Theory

Published in print:
2015
Published Online:
January 2016
ISBN:
9780199300563
eISBN:
9780190299026
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199300563.003.0001
Subject:
Neuroscience, Development

This chapter introduces the core concepts of neural dynamics on which dynamic field theory (DFT) is based. Behavior is generated by the central nervous system (CNS). From this observation, the ... More


Computer- Based Assessment

Philip Schatz

in The Role of Technology in Clinical Neuropsychology

Published in print:
2017
Published Online:
November 2020
ISBN:
9780190234737
eISBN:
9780197559543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190234737.003.0007
Subject:
Computer Science, Virtual Reality

Since the 1950s, academic and researchers have examined artificial intelligence and the use of computers for assistance with, or automation of, data collection (Schatz & Browndyke, 2002). In the ... More


Neuropsychological Late Effects

Raymond K. Mulhern and Robert W. Butler

in Comprehensive Handbook of Childhood Cancer and Sickle Cell Disease: A Biopsychosocial Approach

Published in print:
2006
Published Online:
November 2020
ISBN:
9780195169850
eISBN:
9780197562192
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195169850.003.0020
Subject:
Clinical Medicine and Allied Health, Clinical Oncology

This chapter reviews neuropsychological late effects associated with childhood cancer and its treatment. The study of late effects presupposes that patients are long-term survivors, if not ... More


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