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Methodological and Conceptual Issues in the Study of the Aging Brain

Mark D’Esposito, William Jagust, and Adam Gazzaley

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0002
Subject:
Neuroscience, Techniques, Development

The emergence of functional neuroimaging technology such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) has ushered in a new stage in the study of the aging ... More


BOLD Functional MRI and Cognitive Aging

Adam H. Gazzaley and Mark D’Esposito

in Cognitive Neuroscience of Aging: Linking cognitive and cerebral aging

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195156744
eISBN:
9780199864171
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195156744.003.0005
Subject:
Neuroscience, Behavioral Neuroscience, Development

This chapter focuses on potential confounding factors in the interpretation of the blood oxygen level dependent (BOLD) signal in fMRI studies of cognitive aging. Studies generally attribute ... More


Using ASL to Measure Perfusion Changes in an Individual: Task-Based ASL and Beyond

Michael Chappell, Bradley MacIntosh, and Thomas Okell

in Introduction to Perfusion Quantification using Arterial Spin Labelling

Published in print:
2017
Published Online:
December 2017
ISBN:
9780198793816
eISBN:
9780191835612
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198793816.003.0007
Subject:
Neuroscience, Techniques

Arterial spin labeling (ASL) MRI measurements of perfusion provide a flexible and unique way to study the brain’s physiology and function. They enable experimental designs in neuroimaging that can ... More


The signal

Richard E. Passingham and James B. Rowe

in A Short Guide to Brain Imaging: The Neuroscience of Human Cognition

Published in print:
2015
Published Online:
November 2015
ISBN:
9780198709138
eISBN:
9780191815270
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198709138.003.0002
Subject:
Neuroscience, Behavioral Neuroscience, Development

Whatever brain imaging method is used, it is essential to understand the nature of the measurement that is taken. Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) ... More


Recreational Cannabis: The Risk of Schizophrenia

Paul D. Morrison, Sagnik Bhattacharyya, and Robin M. Murray

in Handbook of Cannabis

Published in print:
2014
Published Online:
January 2015
ISBN:
9780199662685
eISBN:
9780191787560
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199662685.003.0037
Subject:
Neuroscience, Sensory and Motor Systems, Behavioral Neuroscience

Cannabis has been used for millennia, but it was only in 1987 that the first epidemiological evidence emerged which suggested that cannabis was a risk factor for the development of schizophrenia. ... More


Inferences to the Functional Architecture from Functional Imaging

Tim Shallice and Richard P. Cooper

in The Organisation of Mind

Published in print:
2011
Published Online:
March 2015
ISBN:
9780199579242
eISBN:
9780191804489
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:osobl/9780199579242.003.0005
Subject:
Psychology, Cognitive Psychology

This chapter considers anatomically-based methods for the functional imaging of normal subjects. The discussions cover the processing of functional imaging findings; the BOLD measure; the inferential ... More


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