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The Immune Response to Infectious Disease: All Out War!

William R. Clark

in In Defense of Self: How the Immune System Really Works

Published in print:
2008
Published Online:
September 2008
ISBN:
9780195336634
eISBN:
9780199868568
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195336634.003.0005
Subject:
Biology, Disease Ecology / Epidemiology

This chapter deals with the body's response to disease caused by infection with bacteria, viruses, or other microbes. The fundamental response is based on inflammation, which is mediated by the ... More


Journey to the T cell

Jonathan C. Howard

in A Century of Nature: Twenty-One Discoveries that Changed Science and the World

Published in print:
2003
Published Online:
May 2013
ISBN:
9780226284132
eISBN:
9780226284163
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226284163.003.0014
Subject:
History, History of Science, Technology, and Medicine

Immunization against viral infection has saved countless lives, but how it works long remained a mystery. The discovery of antibodies at the end of the nineteenth century revealed one mechanism. ... More


The Non-Hodgkin Lymphomas

James R. Cerhan, Claire M. Vajdic, and John J. Spinelli

in Cancer Epidemiology and Prevention

Published in print:
2017
Published Online:
December 2017
ISBN:
9780190238667
eISBN:
9780190238698
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190238667.003.0040
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

The non-Hodgkin lymphomas (NHL) are a heterogeneous group of over forty lymphoid neoplasms that have undergone a major redefinition over the last twenty-five years, in part due to advances in ... More


Non-Hodgkin Lymphoma

Karin Ekström Smedby, Mads Melbye, and Hans-Olov Adami

in Textbook of Cancer Epidemiology

Published in print:
2018
Published Online:
February 2018
ISBN:
9780190676827
eISBN:
9780190676858
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780190676827.003.0027
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

Non-Hodgkin lymphomas (NHL) are a heterogeneous group of malignancies originating from B- or T-lymphocytes and engaging lymphoid tissue. Clinically, NHL subtypes range from chronic indolent to ... More


FACS-Based High-Throughput Functional Screening of Genetic Libraries for Drug Target Discovery

Erlina Pali and Mark Powell

in Flow Cytometry for Biotechnology

Published in print:
2005
Published Online:
November 2020
ISBN:
9780195183146
eISBN:
9780197561898
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780195183146.003.0016
Subject:
Chemistry, Physical Chemistry

A primary aim of functional genomics in pharmaceutical applications is to identify genes whose function is critical to maintaining a disease state and to determining whether therapeutic modulation ... More


The human immune responses to pertussis and pertussis vaccines

Françoise Mascart, Violette Dirix, and Camille Locht

in Pertussis: Epidemiology, Immunology, and Evolution

Published in print:
2018
Published Online:
February 2019
ISBN:
9780198811879
eISBN:
9780191850011
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198811879.003.0007
Subject:
Biology, Disease Ecology / Epidemiology, Evolutionary Biology / Genetics

Two types of pertussis vaccines are currently available: the first-generation, whole-cell (wP) and more recent, acellular (aP) vaccines. The aP vaccine has replaced the wP vaccine in most ... More


Management of myeloma

Jenny I. O. Craig

in Palliative Care Consultations in Haemato-oncology

Published in print:
2003
Published Online:
November 2011
ISBN:
9780198528081
eISBN:
9780191730399
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198528081.003.0001
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

This chapter discusses myeloma, a clonal B cell disorder that afflicts the elderly with a median age of 69 and with a median survival of three years from diagnosis. Myeloma results from the malignant ... More


Clinical Haematology and Oncology

Iqbal Khan (ed.)

in Best of Five MCQs for the MRCP Part 1 Volume 1

Published in print:
2017
Published Online:
November 2020
ISBN:
9780198746720
eISBN:
9780191916908
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198746720.003.0006
Subject:
Clinical Medicine and Allied Health, Professional Development in Medicine

Questions A 56-year-old woman with terminal breast cancer and spinal metastases comes to the emergency department. She complains of lower back pain and neuopathic pain going down her lefit leg. ... More


The Fightback

Dorothy H. Crawford

in Viruses: The Invisible Enemy

Published in print:
2021
Published Online:
November 2021
ISBN:
9780192845030
eISBN:
9780191937330
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780192845030.003.0002
Subject:
Biology, Animal Biology

This chapter discusses some of the barriers viruses must overcome in order to complete their life cycle. To survive, viruses must penetrate host cells before they can begin the process of reproducing ... More


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