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Introduction

Merton Sandler

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0001
Subject:
Neuroscience, Techniques

It is hard to believe that only ten years have gone by since Peroutka and Snyder's breakthrough in the 5-hydroxytryptamine (5-HT, serotonin) receptor field. There were good precedents with ... More


Monoamines, GABA, Glutamate, and Aggression

Klaus A. Miczek and Eric W. Fish

in Biology of Aggression

Published in print:
2005
Published Online:
May 2009
ISBN:
9780195168761
eISBN:
9780199865444
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195168761.003.0005
Subject:
Neuroscience, Behavioral Neuroscience, Neuroendocrine and Autonomic

This chapter summarizes the evidence describing the roles that monoamines—5-hydroxytryptamine (5-HT), norepinephrine (NE), and dopamine (DA)—exert in the mediation of aggressive behavior. Aggression ... More


Neuroplasticity and Aggression: An Interaction Between Vasopressin and Serotonin

Craig F. Ferris

in Biology of Aggression

Published in print:
2005
Published Online:
May 2009
ISBN:
9780195168761
eISBN:
9780199865444
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195168761.003.0007
Subject:
Neuroscience, Behavioral Neuroscience, Neuroendocrine and Autonomic

This chapter focuses on two neurochemical signals that control aggression—serotonin (5-hydroxytryptamine, or 5-HT) and vasopressin (VP). 5-HT and VP appear to play significant roles in the regulation ... More


5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Merton Sandler, Alec Coppen, and Sara Harnett (eds)

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.001.0001
Subject:
Neuroscience, Techniques

The field of research in 5-hydroxytryptamine has exploded into furious activity over the past decade and nowhere have the implications been more far reaching than in psychiatry. Thanks largely to the ... More


A possible role of endothelial vasorelaxants in the pathogenesis of migraine

Ryszard J. Gryglewski and John R. Vane

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0005
Subject:
Neuroscience, Disorders of the Nervous System

There have been many attempts to explain the pathophysiological mechanism of migraine — for example, the platelet theory, the biogenic amine theory, or the vascular, vaso-neurogenic, and neural ... More


5-HT receptors and migraine

Pramod R. Saxena

in Migraine: A Spectrum of Ideas

Published in print:
1990
Published Online:
March 2012
ISBN:
9780192618108
eISBN:
9780191724305
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192618108.003.0014
Subject:
Neuroscience, Disorders of the Nervous System

Migraine is a vascular headache but its pathophysiology is complex and multifactorial. Of the many pathophysiological factors that are implicated in migraine, changes in the metabolism of ... More


The role of 5-HT in migraine: disentangling the links with depression

Vivette Glover, Joan Jarman, and Merton Sandler

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0007
Subject:
Neuroscience, Techniques

Some disturbance of the 5-hydroxytryptamine (5-HT, serotonin) system has been suggested to be present in a number of clinical conditions that often occur with differing degrees of overlap in affected ... More


Anxiogenic effect of the 5-HT1C agonist m-chlorophenylpiperazine

G. Curzon, G. A. Kennett, and P. Whitton

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0016
Subject:
Neuroscience, Techniques

The earlier literature on l-(3-chlorophenyl)piperazine (m-CPP) and l-[3-(trifluoromethyl)phenyl] piperazine (TFMPP) describes these compounds mainly as agonists at the IB subtype of ... More


5-Hydroxytryptamine in the control of feeding and its possible implications for appetite disturbance

G. Curzon

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0020
Subject:
Neuroscience, Techniques

This chapter focuses on the relationships between 5-hydroxytryptamine (5-HT, serotonin) and feeding and describes both neurochemical and pharmacological findings. Neurochemical research has centred ... More


Disturbance of the 5-hydroxytryptamine metabolism in ageing and in Alzheimer's and vascular dementias

C. G. Gottfries

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0022
Subject:
Neuroscience, Techniques

Syndromes of cognitive, emotional, and psychomotor disturbance in the elderly that are of disabling severity are called dementias and are classified as idiopathic, vascular (VD), and secondary ... More


5-HT3 receptor antagonists and their potential in psychiatric disorders

Michael G. Palfreyman, Stephen M. Sorensen, Albert A. Carr, Hsien C. Cheng, and Mark W. Dudley

in 5-Hydroxytryptamine in Psychiatry: A Spectrum of Ideas

Published in print:
1991
Published Online:
March 2012
ISBN:
9780192620118
eISBN:
9780191724725
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192620118.003.0023
Subject:
Neuroscience, Techniques

Classification of 5-hydroxytryptamine (5-HT, serotonin) receptors in the guinea pig ileum into ‘D’ receptors located on smooth muscle cells and those located on intramural cholinergic neurones of the ... More


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