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Set-Based Gene × Environment Interaction Tests for Complex Diseases with Application to Genome-Wide Association and Sequencing Studies

Shuo Jiao

in Statistical Approaches to Gene X Environment Interactions for Complex Phenotypes

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262034685
eISBN:
9780262335522
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262034685.003.0004
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

This chapter presents set-based approaches that focus on identifying G X E interactions rather than set-based approaches that are based primarily on detecting G main effects (e.g., via marginal ... More


Simulating molecular evolution

Ziheng Yang

in Molecular Evolution: A Statistical Approach

Published in print:
2014
Published Online:
August 2014
ISBN:
9780199602605
eISBN:
9780191782251
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199602605.003.0012
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies, Evolutionary Biology / Genetics

This chapter introduces computer simulation and in particular simulation of the molecular evolutionary process. It covers the generation of random numbers as well as other discrete and continuous ... More


Prelude

M. D. Edge

in Statistical Thinking from Scratch: A Primer for Scientists

Published in print:
2019
Published Online:
October 2019
ISBN:
9780198827627
eISBN:
9780191866463
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198827627.003.0001
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

There are two traditional ways to learn statistics. One way is to pass over the mathematical underpinnings and focus on developing relatively shallow knowledge about a wide variety of statistical ... More


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