Christof Koch
- Published in print:
- 1998
- Published Online:
- November 2020
- ISBN:
- 9780195104912
- eISBN:
- 9780197562338
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/oso/9780195104912.003.0022
- Subject:
- Computer Science, Mathematical Theory of Computation
Some neurons throughout the animal kingdom respond to an intracellular current injection or to an appropriate sensory stimulus with a stereotypical sequence of two to ...
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Some neurons throughout the animal kingdom respond to an intracellular current injection or to an appropriate sensory stimulus with a stereotypical sequence of two to five fast spikes riding upon a slow depolarizing envelope. The entire event, termed a burst, is over within 10-40 msec and is usually terminated by a profound afterhyperpolarization (ΑΗΡ). Such bursting cells are not a random feature of a certain fraction of all cells but can be identified with specific neuronal subpopulations. What are the mechanisms generating this intrinsic firing pattern and what is its meaning? Bursting cells can easily be distinguished from a cell firing at a high maintained frequency by the fact that bursts will persist even at a low firing frequency. As illustrated by the thalamic relay cell of Fig. 9.4, some cells can switch between a mode in which they predominantly respond to stimuli via single, isolated spikes and one in which bursts are common. Because we believe that bursting constitutes a special manner of signaling important information, we devote a single, albeit small chapter to this topic. In the following, we describe a unique class of cells that frequently signal with bursts, and we touch upon the possible biophysical mechanisms that give rise to bursting. We finish this excursion by focussing on a functional study of bursting cells in the electric fish and speculate about the functional relevance of burst firing. Neocortical cells are frequently classified according to their response to sustained current injections. While these distinctions are not all or none, there is broad agreement for three classes: regular spiking, fast spiking, and intrinsically bursting neurons (Connors, Gutnick, and Prince, 1982; McCormick et al., 1985; Connors and Gutnick, 1990; Agmon and Connors, 1992; Baranyi, Szente, and Woody, 1993; Nuńez, Amzica, and Steriade, 1993; Gutnick and Crill, 1995; Gray and McCormick, 1996). Additional cell classes have been identified (e.g., the chattering cells that fire bursts of spikes with interburst intervals ranging from 15 to 50 msec; Gray and McCormick, 1996), but whether or not they occur widely has not yet been settled. The cells of interest to us are the intrinsically bursting cells.
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Some neurons throughout the animal kingdom respond to an intracellular current injection or to an appropriate sensory stimulus with a stereotypical sequence of two to five fast spikes riding upon a slow depolarizing envelope. The entire event, termed a burst, is over within 10-40 msec and is usually terminated by a profound afterhyperpolarization (ΑΗΡ). Such bursting cells are not a random feature of a certain fraction of all cells but can be identified with specific neuronal subpopulations. What are the mechanisms generating this intrinsic firing pattern and what is its meaning? Bursting cells can easily be distinguished from a cell firing at a high maintained frequency by the fact that bursts will persist even at a low firing frequency. As illustrated by the thalamic relay cell of Fig. 9.4, some cells can switch between a mode in which they predominantly respond to stimuli via single, isolated spikes and one in which bursts are common. Because we believe that bursting constitutes a special manner of signaling important information, we devote a single, albeit small chapter to this topic. In the following, we describe a unique class of cells that frequently signal with bursts, and we touch upon the possible biophysical mechanisms that give rise to bursting. We finish this excursion by focussing on a functional study of bursting cells in the electric fish and speculate about the functional relevance of burst firing. Neocortical cells are frequently classified according to their response to sustained current injections. While these distinctions are not all or none, there is broad agreement for three classes: regular spiking, fast spiking, and intrinsically bursting neurons (Connors, Gutnick, and Prince, 1982; McCormick et al., 1985; Connors and Gutnick, 1990; Agmon and Connors, 1992; Baranyi, Szente, and Woody, 1993; Nuńez, Amzica, and Steriade, 1993; Gutnick and Crill, 1995; Gray and McCormick, 1996). Additional cell classes have been identified (e.g., the chattering cells that fire bursts of spikes with interburst intervals ranging from 15 to 50 msec; Gray and McCormick, 1996), but whether or not they occur widely has not yet been settled. The cells of interest to us are the intrinsically bursting cells.
Patrick D. Bowen
- Published in print:
- 2020
- Published Online:
- February 2021
- ISBN:
- 9780190853884
- eISBN:
- 9780190853914
- Item type:
- chapter
- Publisher:
- Oxford University Press
- DOI:
- 10.1093/oso/9780190853884.003.0008
- Subject:
- Religion, Religious Studies
This chapter demonstrates how yoga was introduced to Western readers interested in occultism and the East in the pages of The Theosophist in the early 1880s. In 1885, the newly formed occult society ...
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This chapter demonstrates how yoga was introduced to Western readers interested in occultism and the East in the pages of The Theosophist in the early 1880s. In 1885, the newly formed occult society the Hermetic Brotherhood of Luxor (HB of L), which took inspiration from Theosophy, began instructing its members to read about and practice Theosophy-connected forms of yoga as a way to prepare for occult initiation. It was presumably the first society to do so. Using newly unearthed letters of early members of the Theosophical Society and the HB of L, the chapter pioneeringly traces the early history of the introduction of the practice of yoga in these organizations, which later, through Rev. William Ayton, led to Aleister Crowley and other British occultists’ interest in yoga.Less
This chapter demonstrates how yoga was introduced to Western readers interested in occultism and the East in the pages of The Theosophist in the early 1880s. In 1885, the newly formed occult society the Hermetic Brotherhood of Luxor (HB of L), which took inspiration from Theosophy, began instructing its members to read about and practice Theosophy-connected forms of yoga as a way to prepare for occult initiation. It was presumably the first society to do so. Using newly unearthed letters of early members of the Theosophical Society and the HB of L, the chapter pioneeringly traces the early history of the introduction of the practice of yoga in these organizations, which later, through Rev. William Ayton, led to Aleister Crowley and other British occultists’ interest in yoga.
Mauro Carbone
- Published in print:
- 2020
- Published Online:
- January 2021
- ISBN:
- 9780823288137
- eISBN:
- 9780823290376
- Item type:
- chapter
- Publisher:
- Fordham University Press
- DOI:
- 10.5422/fordham/9780823288137.003.0002
- Subject:
- Philosophy, General
In The Visible and the Invisible, Merleau-Ponty famously wrote: “No one has gone further than Proust in fixing the relations between the visible and the invisible.” To gain a fresh and original ...
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In The Visible and the Invisible, Merleau-Ponty famously wrote: “No one has gone further than Proust in fixing the relations between the visible and the invisible.” To gain a fresh and original access to Merleau-Ponty’s interpretation of Proust, this chapter places his views alongside those of another of Proust’s great interpreters, Walter Benjamin. In spite of the absence of explicit references to Benjamin in the writings of Merleau-Ponty, certain intersections are clear. For one thing, we find the originating importance of Husserl for Merleau-Ponty and Benjamin. Though they make reference to very distant periods of Husserlian thought, they share at least a distrust with regard to experience understood as Erlebnis. Second, they each give attention to the theme of essence and ideas, which, concerning artistic and literary works, are considered by the two thinkers as immanent within the works themselves. This suggests one of the most important contributions of Proust to Merleau-Ponty’s thought, the concept of “sensible ideas.” Third, both Merleau-Ponty and Benjamin demonstrate their common interest in perception and memory, sometimes focusing on the very same pages of Recherche du temps perdu [In Search of Lost Time] to deepen, through the character of Marcel, the concept of “involuntary memory.”Less
In The Visible and the Invisible, Merleau-Ponty famously wrote: “No one has gone further than Proust in fixing the relations between the visible and the invisible.” To gain a fresh and original access to Merleau-Ponty’s interpretation of Proust, this chapter places his views alongside those of another of Proust’s great interpreters, Walter Benjamin. In spite of the absence of explicit references to Benjamin in the writings of Merleau-Ponty, certain intersections are clear. For one thing, we find the originating importance of Husserl for Merleau-Ponty and Benjamin. Though they make reference to very distant periods of Husserlian thought, they share at least a distrust with regard to experience understood as Erlebnis. Second, they each give attention to the theme of essence and ideas, which, concerning artistic and literary works, are considered by the two thinkers as immanent within the works themselves. This suggests one of the most important contributions of Proust to Merleau-Ponty’s thought, the concept of “sensible ideas.” Third, both Merleau-Ponty and Benjamin demonstrate their common interest in perception and memory, sometimes focusing on the very same pages of Recherche du temps perdu [In Search of Lost Time] to deepen, through the character of Marcel, the concept of “involuntary memory.”