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Metals in the Environment as Risk Factors for Infectious Diseases: Gaps and Opportunities

M. Leigh Ackland, Julia Bornhorst, George V. Dedoussis, Rodney R. Dietert, Jerome O. Nriagu, Jozef M. Pacyna, and John M. Pettifor

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0017
Subject:
Public Health and Epidemiology, Public Health

By reducing immune function, trace metal deficiencies may substantially contribute to the global burden of diarrhea, pneumonia, and malaria. Human activities may be contributing to trace metal ... More


Impact of Metals on Immune Response and Tolerance, and Modulation of Metal Metabolism during Infection

Günter Weiss

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0009
Subject:
Public Health and Epidemiology, Public Health

Several metals play important roles in host cell and microbial metabolism because they form a part of central enzymes that are essential, for example, for DNA synthesis, cellular respiration, and key ... More


Trace Metals in Host–Microbe Interactions: The Microbe Perspective

Jennifer S. Cavet, Robert D. Perry, Sascha Brunke, K. Heran Darwin, Carol A. Fierke, James A. Imlay, Michael E. P. Murphy, Anthony B. Schryvers, Dennis J. Thiele, and Jeffrey N. Weiser

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0007
Subject:
Public Health and Epidemiology, Public Health

Microbes must acquire metals for metabolic processes, with nearly a half of all enzymes requiring a metal cofactor for function, yet microbes can be poisoned by metals. The host innate immune ... More


Impact of Lifestyle on Metal Exposure, Homeostasis, and Associated Diseases

George V. Dedoussis

in Trace Metals and Infectious Diseases

Published in print:
2015
Published Online:
May 2016
ISBN:
9780262029193
eISBN:
9780262327619
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029193.003.0011
Subject:
Public Health and Epidemiology, Public Health

Unhealthy lifestyle factors (e.g., cigarette smoking, excessive alcohol consumption, long working hours, reduced sleep, physical inactivity, obesogenic diets) and psychological stress contribute to ... More


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