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Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State

Joachim Frank

Published in print:
2006
Published Online:
April 2010
ISBN:
9780195182187
eISBN:
9780199893416
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195182187.001.0001
Subject:
Biology, Biochemistry / Molecular Biology

In this book, the mathematical principles and working methods of single-particle reconstruction are described; a method designed to retrieve three-dimensional structural information from electron ... More


The Light Microscope

Peter B. Moore

in Visualizing the Invisible: Imaging Techniques for the Structural Biologist

Published in print:
2012
Published Online:
May 2015
ISBN:
9780199767090
eISBN:
9780190267841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:osobl/9780199767090.003.0010
Subject:
Biology, Biochemistry / Molecular Biology

This chapter begins by identifying various kinds of imaging techniques. It then examines the role played by the amount of light and presence of fluorophore in the imaging process. the latter part of ... More


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