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Genetic epidemiology

Harry Campbell and Susan Service

in Teaching Epidemiology: A guide for teachers in epidemiology, public health and clinical medicine

Published in print:
2010
Published Online:
May 2010
ISBN:
9780199239481
eISBN:
9780191716973
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199239481.003.012
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

A major challenge for epidemiology in the future is understanding the role of genetic risk factors and how genetic factors interact with environmental factors in causing disease. There is a clear ... More


Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Muin Khoury, Sara Bedrosian, Marta Gwinn, Julian Higgins, John Ioannidis, and Julian Little (eds)

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.001.0001
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery ... More


Genes as a Source of Risk for Mental Disorders

Peter P. Zandi, Holly C. Wilcox, Lulu Dong, Sandy Chon, and Brion Maher

in Public Mental Health

Published in print:
2012
Published Online:
September 2012
ISBN:
9780195390445
eISBN:
9780199950416
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195390445.003.0008
Subject:
Public Health and Epidemiology, Public Health

This chapter explores the current understanding of how genetic factors contribute to human mental health in general, and in particular how they lead to disturbances that can affect public mental ... More


Navigating the evolving knowledge of human genetic variation in health and disease

Marta Gwinn and Wei Yu

in Human Genome Epidemiology, 2nd Edition: Building the evidence for using genetic information to improve health and prevent disease

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195398441
eISBN:
9780199776023
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195398441.003.0004
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter presents an overview of evolving methods for tracking and compiling information on genetic factors in disease. It discusses bioinformatics, the Human Genome Epidemiology Network ... More


Genetic Predictors of Obesity

Frank B. Hu

in Obesity Epidemiology

Published in print:
2008
Published Online:
September 2009
ISBN:
9780195312911
eISBN:
9780199865260
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195312911.003.0021
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter begins with a review of the genetic factors underlying monogenic and syndromic forms of obesity. It describes the genetics of common obesity, with a particular focus on results from ... More


Neurodevelopmental Disabilities

Lorene M. Nelson, Caroline M. Tanner, Stephen K. Van Den Eeden, and Valerie M. McGuire

in Neuroepidemiology: From principles to practice

Published in print:
2004
Published Online:
September 2009
ISBN:
9780195133790
eISBN:
9780199863730
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195133790.003.15
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The topic of this chapter is neurodevelopmental disabilities, with discussion focused on three prototypic neurodevelopmental disorders: mental retardation, autism, and cerebral palsy. These disorders ... More


Applying genetic strategies to prevent atherosclerosis

Roger R. Williams, Paul N. Hopkins, Lily L. Wu, and Steven C. Hunt

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0024
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Atherosclerotic disease of coronary and cerebral arteries accounts for almost half of all deaths in the United States each year. Heart attacks and strokes are often attributable to inherited ... More


Public health assessment of genetic susceptibility to infectious diseases: malaria, tuberculosis, and HIV

Janet M McNicholl, Marie V. Downer, Michael Aidoo, Thomas Hodge, and Venkatachalam Udhayakumar

in Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease

Published in print:
2000
Published Online:
September 2009
ISBN:
9780195128307
eISBN:
9780199864485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195128307.003.0010
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The understanding of the host genetic factors that influence susceptibility to and the course of infectious diseases is growing rapidly. Even for the most common pathogens, however, there is an ... More


Alcohol

JAMES R. MARSHALL and JO FREUDENHEIM

in Cancer Epidemiology and Prevention

Published in print:
2006
Published Online:
September 2009
ISBN:
9780195149616
eISBN:
9780199865062
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195149616.003.0014
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter begins by summarizing current understanding of the mechanisms by which alcohol might affect cancer risk and then evaluates the molecular genetic factors that appear relevant to alcohol ... More


Genetics in Dietary Analyses

Walter Willett

in Nutritional Epidemiology

Published in print:
2012
Published Online:
January 2013
ISBN:
9780199754038
eISBN:
9780199979448
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199754038.003.0014
Subject:
Public Health and Epidemiology, Epidemiology, Public Health

Nutritionists have long known that differences exist among individuals in their responses to the same dietary change, and it was assumed that many of these differences were due to unmeasurable ... More


Future Research Directions

Walter Willett

in Nutritional Epidemiology

Published in print:
1998
Published Online:
September 2009
ISBN:
9780195122978
eISBN:
9780199864249
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195122978.003.19
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter outlines future directions on nutritional epidemiology. Topics covered include development of prospective cohort dietary studies, validation studies, case-control studies in nutritional ... More


Epilepsy

Lorene M. Nelson, Caroline M. Tanner, Stephen K. Van Den Eeden, and Valerie M. McGuire

in Neuroepidemiology: From principles to practice

Published in print:
2004
Published Online:
September 2009
ISBN:
9780195133790
eISBN:
9780199863730
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195133790.003.12
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter begins with a discussion of the taxonomy of seizure disorders and the clinical features of epilepsy that pose methodological challenges in clinical and epidemiologic studies. Descriptive ... More


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