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Human Population Genomics and the Dilemma of Difference

Jenny Reardon

in Reframing Rights: Bioconstitutionalism in the Genetic Age

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015950
eISBN:
9780262298667
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015950.003.0114
Subject:
Biology, Bioethics

This chapter introduces the theme of bottom-up agency with an account of struggles for authority between socially and scientifically constituted groups of genetic research subjects. It addresses how ... More


Electron density fitting and structure validation

Mike Carson

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0013
Subject:
Biology, Biochemistry / Molecular Biology

The Human Genome Project went three-dimensional in late 2000. ‘Structural genomics’ efforts will determine the structures of thousands of new proteins over the few years. These initiatives seek to ... More


Statistical Approaches to Gene X Environment Interactions for Complex Phenotypes

Michael Windle (ed.)

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262034685
eISBN:
9780262335522
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262034685.001.0001
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

Findings from the Human Genome Project and from Genome-Wide Association (GWA) studies indicate that many diseases and traits manifest a more complex genomic pattern than previously assumed. These ... More


GenomicsXSlot Machines

Mike Fortun

in Promising Genomics: Iceland and deCODE Genetics in a World of Speculation

Published in print:
2008
Published Online:
March 2012
ISBN:
9780520247505
eISBN:
9780520942615
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520247505.003.0021
Subject:
Biology, Evolutionary Biology / Genetics

The Human Genome Project had overemphasized and overproduced what William Haseltine, CEO of Human Genome Sciences Inc., called “genetic genomics,” privileging the reference sequence for the human ... More


A Future Bright and Dark

Lynn C. Klotz and Edward J. Sylvester

in Breeding Bio Insecurity: How U.S. Biodefense Is Exporting Fear, Globalizing Risk, and Making Us All Less Secure

Published in print:
2009
Published Online:
February 2013
ISBN:
9780226444055
eISBN:
9780226444079
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226444079.003.0002
Subject:
Biology, Biotechnology

Discoveries in molecular biology are changing the understanding of human complexity and unraveling these newfound complexities requires emerging disciplines such as systems biology. Some strategies ... More


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