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NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

W. Otto Friesen and Jonathon Friesen

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.001.0001
Subject:
Psychology, Cognitive Neuroscience

The electrical membrane potential is an important property for the functioning of living cells. Temporal variations of this potential generated by synaptic interactions and expressed as nerve ... More


Axon Models

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0011
Subject:
Psychology, Cognitive Neuroscience

The Axon model simulates the equations and parameters derived from experiments by Hodgkin and Huxley on the squid giant axon. Because of the exact correspondence between the equations incorporated ... More


Basis of the Nerve Impulse

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0004
Subject:
Psychology, Cognitive Neuroscience

The rapid conduction of signals by neurons over distances greater than about 1 mm occurs almost exclusively by electrical impulses. This chapter presents the fundamental concepts that underlie the ... More


Voltage-clamp studies in axons: Macroscopic and single-channel currents

WERNER VOGEL and JÜRGEN R. SCHWARZ

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0013
Subject:
Neuroscience, Disorders of the Nervous System

This chapter describes macroscopic membrane currents measured in amphibian and mammalian nodes of Ranvier with the voltage-clamp method. These results are compared with those of single-channel ... More


Galvani’s Spark: The Story of the Nerve Impulse

Alan McComas

Published in print:
2011
Published Online:
September 2011
ISBN:
9780199751754
eISBN:
9780199897094
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199751754.001.0001
Subject:
Neuroscience, History of Neuroscience, Sensory and Motor Systems

The nerve impulse is the basis of all human thoughts and emotions, and of all sensations and movements. As such, it has been the subject of scientific enquiry for more than two centuries, beginning ... More


Introduction

Alan J. McComas

in Galvani’s Spark: The Story of the Nerve Impulse

Published in print:
2011
Published Online:
September 2011
ISBN:
9780199751754
eISBN:
9780199897094
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199751754.003.0001
Subject:
Neuroscience, History of Neuroscience, Sensory and Motor Systems

Nerve impulses traversing the brain were likened by Sherrington to points of light in an enchanted loom. The electrochemical nature of the nerve impulse was largely elucidated by Hodgkin and Huxley ... More


The Voltage Clamp

Alan J. McComas

in Galvani’s Spark: The Story of the Nerve Impulse

Published in print:
2011
Published Online:
September 2011
ISBN:
9780199751754
eISBN:
9780199897094
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199751754.003.0015
Subject:
Neuroscience, History of Neuroscience, Sensory and Motor Systems

Now in Chicago, Kenneth Cole employs a negative feedback circuit, devised by a colleague, to clamp the voltage across the membrane of the squid giant axon. He shows that during the action potential ... More


An improved voltage clamp for gating current recording from the squid giant axon

Ian C. Forster and Nikolaus G. Greeff

in Cephalopod Neurobiology: Neuroscience Studies in Squid, Octopus and Cuttlefish

Published in print:
1995
Published Online:
March 2012
ISBN:
9780198547907
eISBN:
9780191724299
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198547907.003.0070
Subject:
Neuroscience, Invertebrate Neurobiology

This chapter deals with three aspects of cylindrical voltage-clamp designs, namely, dynamic response, noise performance, and system linearity. The clamp dynamic performance affects both the speed and ... More


Ion channels: Principles, terminology and methodology

Derek Trezise, Tim Dale, and Martin Main

in Ion Channels: From Structure to Function

Published in print:
2009
Published Online:
March 2012
ISBN:
9780199296750
eISBN:
9780191724572
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199296750.003.0001
Subject:
Neuroscience, Development

Ion channels are cellular proteins that conduct the movement of ions from one side of a membrane to the other. The resultant changes in local ion concentrations and electrical field play pivotal ... More


Active Behavior of the Membrane

Jaakko Malmivuo

in Bioelectromagnetism: Principles and Applications of Bioelectric and Biomagnetic Fields

Published in print:
1995
Published Online:
March 2012
ISBN:
9780195058239
eISBN:
9780199847839
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195058239.003.0004
Subject:
Neuroscience, Techniques

This chapter describes the voltage clamp device, the experiments of Hodgkin and Huxley, the mathematical model into which their data were fitted, and the resulting simulation of a wide variety of ... More


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