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Synapse Model

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0013
Subject:
Psychology, Cognitive Neuroscience

The Synapse model simulates the membrane potentials of three-compartment invertebrate neurons, comprising a soma, the neurite, and an axon. This model includes synaptic conductances to simulate ... More


Equations Underlying the Synapse Model

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0021
Subject:
Psychology, Cognitive Neuroscience

The Synapse model illustrates synaptic interactions among neurons. This chapter provides the equations for electrical coupling, for inhibitory and excitatory synaptic interactions, and for synaptic ... More


Electrophysiology of Neuronal Interactions

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0006
Subject:
Psychology, Cognitive Neuroscience

Two aspects of electrophysiology are critical for the functioning of the nervous system — the properties of individual neurons and the properties of synaptic interactions. The cell doctrine, that ... More


Motoneurones: synaptic control

Daniel Kernell

in The Motoneurone and its Muscle Fibres

Published in print:
2006
Published Online:
September 2009
ISBN:
9780198526551
eISBN:
9780191723896
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198526551.003.0007
Subject:
Neuroscience, Molecular and Cellular Systems

The cell body and dendrites of a motoneurone are covered with thousands of synaptic boutons, and the ultrastructure of the boutons is generally thought to be related to their functional ... More


Beyond Neurotransmission: Neuromodulation and its Importance for Information Processing

Paul Katz (ed.)

Published in print:
1999
Published Online:
March 2012
ISBN:
9780198524243
eISBN:
9780191724435
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198524243.001.0001
Subject:
Neuroscience, Behavioral Neuroscience

There are many modes of communication that neurons use to transmit information besides what has come to be called neurotransmission. Many of these other types of communication can be classified as ... More


The Synapse: Function, Plasticity, and Neurotrophism

Motoy Kuno

Published in print:
1994
Published Online:
March 2012
ISBN:
9780198546870
eISBN:
9780191724350
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198546870.001.0001
Subject:
Neuroscience, Molecular and Cellular Systems

The synapse not only provides a bridge from one nerve cell to the next; its function can be modified by experience, making it important for learning and memory. This overview of the synapse provides ... More


Synapse formation: a molecular perspective

Joshua R. Sanes and Richard H. Scheller

in Molecular and Cellular Approaches to Neural Development

Published in print:
1998
Published Online:
May 2009
ISBN:
9780195111668
eISBN:
9780199865833
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195111668.003.0005
Subject:
Neuroscience, Molecular and Cellular Systems, Development

This chapter reviews recent molecular analyses of neuromuscular synaptogenesis, focusing on vertebrate synapses. It summarizes the extensive histological and electrophysiological studies have provide ... More


Creating Modern Neuroscience: The Revolutionary 1950s

Gordon M. Shepherd MD, DPhil

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.001.0001
Subject:
Neuroscience, History of Neuroscience

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, ... More


Cell Biology and the Synapse

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0005
Subject:
Neuroscience, History of Neuroscience

Before the 1950s, cell structure could be studied only under the light microscope, and the organelles that do the work of the cell were seen only indistinctly. By the end of the 1950s, the electron ... More


Physiology: Synaptic Potentials and Receptor Potentials

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0007
Subject:
Neuroscience, History of Neuroscience

This chapter details early studies on synaptic and reception potentials. After excitability, the second key property of nerve cells is the action that occurs at the synapses between cells. This is ... More


Functional Organization of Neurons and Dendrites

Gordon M. Shepherd

in Creating Modern Neuroscience: The Revolutionary 1950s

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195391503
eISBN:
9780199863464
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195391503.003.0008
Subject:
Neuroscience, History of Neuroscience

This chapter details early studies on the neuron doctrine. The neuron doctrine arose as an organizing principle for the nervous system in the late 19th century. The advances in the 1950s provided the ... More


The Motoneurone and its Muscle Fibres

Daniel Kernell

Published in print:
2006
Published Online:
September 2009
ISBN:
9780198526551
eISBN:
9780191723896
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198526551.001.0001
Subject:
Neuroscience, Molecular and Cellular Systems

This book presents a summary of knowledge concerning somatic motoneurones, the cells which link the central nervous system to the skeletal muscles. There are two functional kinds of such ... More


Molecular biology of neurotransmitter release

Julie Staple and Stefan Catsicas

in Molecular Biology of the Neuron

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198509981
eISBN:
9780191723810
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509981.003.0006
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter discusses modern concepts in neurotransmitter release, and learning and synapses. Fusion and re-uptake of specialized membrane is involved in a number of processes which affect neuronal ... More


Number in electron microscopy: estimation of total number of synapses in the main regions of human neocortex

Jens R. Nyengaard, Karl-Anton Dorph-Petersen, and Yong Tang

in Quantitative Methods in Neuroscience: A Neuroanatomical Approach

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198505280
eISBN:
9780191723766
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198505280.003.0006
Subject:
Neuroscience, Techniques

Significant disagreements exist among previous morphometric studies of synapse number in relation to memory deficits associated with aging and diseases such as Alzheimer's disease. There may be a ... More


Interneuronal Variability: Plasticity and Regulation

Ivan Soltesz

in Diversity in the Neuronal Machine: Order and Variability in Interneuronal Microcircuits

Published in print:
2006
Published Online:
May 2009
ISBN:
9780195177015
eISBN:
9780199864713
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195177015.003.0006
Subject:
Neuroscience, Neuroendocrine and Autonomic, Techniques

This chapter shows that somatic mutations in the brain may be more frequent than previously believed, and they may result in substantial alterations in synaptic functions involved in learning and ... More


Neuromuscular transmission

Daniel Kernell

in The Motoneurone and its Muscle Fibres

Published in print:
2006
Published Online:
September 2009
ISBN:
9780198526551
eISBN:
9780191723896
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198526551.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems

The connection between motoneuronal axons and skeletal muscle fibres (neuromuscular junction, NMJ) shares basic characteristics with many excitatory chemical synapses inside the central nervous ... More


Introduction

Edmund T. Rolls

in Memory, Attention, and Decision-Making: A Unifying Computational Neuroscience Approach

Published in print:
2007
Published Online:
September 2009
ISBN:
9780199232703
eISBN:
9780191724046
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199232703.003.0001
Subject:
Neuroscience, Behavioral Neuroscience

This introductory chapter discusses neurons, neurons in a network, synaptic modification, long-term potentiation and long-term depression, and distributed representations. It also details the fine ... More


The Developing Brain and Adolescent-Typical Behavior Patterns: An Evolutionary Approach

Linda Spear

in Adolescent Psychopathology and the Developing Brain: Integrating Brain and Prevention Science

Published in print:
2007
Published Online:
May 2009
ISBN:
9780195306255
eISBN:
9780199863914
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195306255.003.0001
Subject:
Neuroscience, Development

This chapter reviews current knowledge about the adolescent period from the perspective of evolutionary biology and the study of mammals, including humans. It highlights the universal characteristics ... More


Introduction to Synaptic Circuits

GORDON M. SHEPHERD

in The Synaptic Organization of the Brain

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195159561
eISBN:
9780199864447
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195159561.003.0001
Subject:
Neuroscience, Molecular and Cellular Systems, Development

This chapter introduces some of the basic principles that are common to the different regions of the brain. It shows that it is possible to identify fundamental types of synaptic circuits at ... More


Historical Perspective: Proposed Functions, Biological Characteristics, and Neurobiological Models of the Hippocampus

Andersen Per, Morris Richard, Amaral David, Bliss Tim, and O’Keefe John

in The Hippocampus Book

Published in print:
2006
Published Online:
May 2009
ISBN:
9780195100273
eISBN:
9780199864133
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195100273.003.0002
Subject:
Neuroscience, Molecular and Cellular Systems, Behavioral Neuroscience

This chapter presents a historical discussion of the key discoveries and concepts of hippocampal neurobiology of the modern era up to about the 1970s. It is divided into two main sections. The first ... More


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