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Protein Misfolding, Mitochondrial Disturbances, And Kynurenines In The Pathogenesis Of Neurodegenerative Disorders

Gabriella Gárdián, Katalin Sas, József Toldi, and László Vécsei

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0018
Subject:
Neuroscience, Molecular and Cellular Systems

As a population ages, neurodegenerative diseases become increasingly prevalent. These are different clinical entities, though they display many common features in their clinical, biochemical, and ... More


The neuropsychological presentation of Alzheimer’s disease and other neurodegenerative disorders

Julie Snowden

in The Handbook of Clinical Neuropsychology

Published in print:
2010
Published Online:
September 2010
ISBN:
9780199234110
eISBN:
9780191594250
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199234110.003.028
Subject:
Psychology, Neuropsychology, Clinical Psychology

Alzheimer's disease and other neurodegenerative diseases that lead to progressive cognitive impairment are conventionally classified as ‘the dementias’. Dementia is traditionally defined as a ... More


Family carers of people with advanced organ failure and neurodegenerative disorders

Janice Brown and Julia Addingto-Hall

in Family Carers in Palliative Care: A guide for health and social care professionals

Published in print:
2008
Published Online:
November 2011
ISBN:
9780199216901
eISBN:
9780191730252
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199216901.003.0013
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Palliative Medicine Research

This chapter examines the needs, conditions, and experiences of family carers of people with neurodegenerative disorders and advanced organ failure. It focuses on six disorders which currently ... More


The Neuroscience of Cruelty as Brain Damage: Legal Framings of Capacity and Ethical Issues in the Neurorehabilitation of Motor Neurone Disease and Behavioural Variant Frontotemporal Dementia

Robin Mackenzie and Mohamed Sakel

in Law and Neuroscience: Current Legal Issues Volume 13

Published in print:
2011
Published Online:
May 2011
ISBN:
9780199599844
eISBN:
9780191725227
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199599844.003.0015
Subject:
Law, Medical Law

This chapter explores some ethical and legal issues arising from the impact of the neuroscience of decision-making and emotion on end-of-life decisions of patients with certain neurodegenerative ... More


Huntington's disease and dementia

Belinda Bilney and Meg E. Morris

in Supportive care for the person with dementia

Published in print:
2009
Published Online:
November 2011
ISBN:
9780199554133
eISBN:
9780191730269
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199554133.003.0007
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

Huntington's disease (HD) is an inherited neurodegenerative disorder for which there is currently no known cure. Disease onset usually occurs around thirty-five to forty-five years of age and may be ... More


Distinguishing among motor speech disorders is important: the role of speech pathology in neurologic diagnosis

Joseph R. Duffy

in Speech Motor Control: New developments in basic and applied research

Published in print:
2010
Published Online:
March 2012
ISBN:
9780199235797
eISBN:
9780191696671
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235797.003.0016
Subject:
Neuroscience, Sensory and Motor Systems

The contribution that distinguishing among motor speech disorders (MSDs) can make to the localization and diagnosis of neurological disease is frequently ignored by medicine and, at the least, ... More


Biomedical Odysseys: Fetal Cell Experiments from Cyberspace to China

Priscilla Song

Published in print:
2017
Published Online:
May 2018
ISBN:
9780691174778
eISBN:
9781400885282
Item type:
book
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691174778.001.0001
Subject:
Anthropology, Social and Cultural Anthropology

Thousands of people from more than eighty countries have traveled to China since 2001 to undergo fetal cell transplantation. Galvanized by the potential of stem and fetal cells to regenerate damaged ... More


Competitive NMDA antagonists as drugs

B. S. MELDRUM and A. G. CHAPMAN

in The NMDA Receptor

Published in print:
1995
Published Online:
March 2012
ISBN:
9780192625021
eISBN:
9780191724701
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192625021.003.0019
Subject:
Neuroscience, Molecular and Cellular Systems

The potential clinical applications of N-methyl-d-aspartate (NMDA) antagonists were initially defined on the basis of animal models. Epilepsy was the first target syndrome identified and remains an ... More


Competence for Informed Consent for Treatment and Research

Scott Y. H. Kim

in Neuroethics in Practice

Published in print:
2013
Published Online:
May 2013
ISBN:
9780195389784
eISBN:
9780199979233
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195389784.003.0007
Subject:
Neuroscience, Behavioral Neuroscience

Modern medical ethics and law place a very high value on individual autonomy. But the prevalence of decision-making incapacity-i.e., when a person lacks the capacity to exercise that autonomy-will ... More


On Parkinson’s Disease

Patrick McNamara

in The Cognitive Neuropsychiatry of Parkinson's Disease

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262016087
eISBN:
9780262298360
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262016087.003.0001
Subject:
Psychology, Cognitive Neuroscience

This chapter defines Parkinson’s disease for readers who are unfamiliar with this degenerative disease, which affects the brain, adversely impacting activities that are controlled by the central ... More


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