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Brain Inflammation and the Neuronal Fate: from Neurogenesis to Neurodegeneration

Maria Antonietta Ajmone-Cat, Emanuele Cacci, and Luisa Minghetti

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0013
Subject:
Neuroscience, Molecular and Cellular Systems

Inflammation is a self-defensive reaction that may develop into a chronic state and become a causative factor in the pathogenesis of a broad range of disabling diseases. Similar to peripheral ... More


Regenerating the Brain

Walter Glannon

in Brain, Body, and Mind: Neuroethics with a Human Face

Published in print:
2011
Published Online:
May 2011
ISBN:
9780199734092
eISBN:
9780199894475
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199734092.003.0017
Subject:
Philosophy, Moral Philosophy

This chapter examines neural cell replacement therapy for neurodegenerative diseases and spinal cord injury. While neural transplantation has the potential to regenerate the brain, results from ... More


Selective Neuronal Vulnerability in the Hippocampus: Relationship to Neurological Diseases and Mechanisms for Differential Sensitivity of Neurons to Stress

Elias K. Michaelis

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0004
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

The phenomenon of selective neuronal vulnerability to neurological diseases or insults, such as ischemia-reperfusion, brain trauma, and ageing-associated neurodegeneration, was described in the ... More


Neurodegenerative disease: With Harry Baker

James W. Fawcett, Anne E. Rosser, and Stephen B. Dunnett

in Brain Damage, Brain Repair

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198523376
eISBN:
9780191724534
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198523376.003.0006
Subject:
Neuroscience, Techniques

Most dementias are associated with a widespread pattern of atrophy in the forebrain, which is most apparent as a reduction in the weight of the brain measured post-mortem. As the brain undergoes loss ... More


A Cognitive and Behavioral Neurological Approach to Aesthetics

Zachary A. Miller and Bruce L. Miller

in Aesthetic Science: Connecting Minds, Brains, and Experience

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199732142
eISBN:
9780199918485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199732142.003.0079
Subject:
Psychology, Cognitive Psychology

Philosophers have hypothesized that one of the defining characteristics of being human is the production and appreciation of art. Beginning in the early 20th century, observations following isolated ... More


Role of Prion Protein During Normal Physiology and Disease

Adriana Simon Coitinho and Glaucia N. M. Hajj

in Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging

Published in print:
2009
Published Online:
January 2010
ISBN:
9780195326697
eISBN:
9780199864874
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195326697.003.0001
Subject:
Neuroscience, Molecular and Cellular Systems

Prions are infectious particles composed only of proteins. Their importance resides in the concept that information transmission between two organisms can be devoid of nucleic acid. Prions are also ... More


Immune Responses in the Nervous System

Nancy J. Rothwell (ed.)

Published in print:
1997
Published Online:
March 2012
ISBN:
9781872748795
eISBN:
9780191724381
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9781872748795.001.0001
Subject:
Neuroscience, Disorders of the Nervous System

This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and ... More


Immune and Inflammatory Responses in the Nervous System

Nancy Rothwell and Sarah Loddick (eds)

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198509806
eISBN:
9780191724596
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509806.001.0001
Subject:
Neuroscience, Disorders of the Nervous System

This new edition covers advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms ... More


Breathlessness in neurological disease

Fliss Murtagh, Rachel Burman, and Polly Edmonds

in Dyspnoea in Advanced Disease: A guide to clinical management

Published in print:
2005
Published Online:
November 2011
ISBN:
9780198530039
eISBN:
9780191730450
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198530039.003.0006
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

While some aspects of breathlessness in neurological disease are common to various neurological diseases, some aspects are specific to particular ones. This chapter therefore addresses the ... More


Cortical Lewy body disease: dementia with Lewy bodies and Parkinson's disease with dementia

John E. Duda and Ian G. McKeith

in Cognitive Neurology: A clinical textbook

Published in print:
2008
Published Online:
March 2012
ISBN:
9780198569275
eISBN:
9780191724213
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198569275.003.0015
Subject:
Neuroscience, Techniques

One of the most hotly debated topics in the field of neurodegenerative disease is the relationship between what has recently been described as dementia with Lewy bodies (DLB) and the condition of ... More


New Frontiers in Cognitive Aging

Roger Dixon, Lars Backman, and Lars-Goran Nilsson (eds)

Published in print:
2004
Published Online:
March 2012
ISBN:
9780198525691
eISBN:
9780191689369
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198525691.001.0001
Subject:
Psychology, Cognitive Psychology

With an ever increasing population of aging people in the western world, it is more crucial than ever that we try to understand how and why cognitive competence breaks down with advancing age; why do ... More


How Do We Define and Modulate Circuits in Animals That Are Relevant to Pathophysiology in Humans?

Joel S. Perlmutter

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0009
Subject:
Neuroscience, Research and Theory

How do investigators define and modulate circuits in animals that are relevant to the pathophysiology of human neurodegenerative diseases? Animal models provide a variety of advantages for ... More


Environmental Influences on Neurodegenerative Disease: The Impact of Systemic Inflammation

Hugh Perry V.

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0025
Subject:
Neuroscience, Research and Theory

This chapter deals with the effect of systemic inflammation on neurodegenerative disease. It demonstrates that inflammation may contribute to Alzheimer’s disease (AD) progression. This chapter shows ... More


Episodic-like memory in animals: psychological criteria, neural mechanisms and the value of episodic-like tasks to investigate animal models of neurodegenerative disease

Richard G. M. Morris

in Episodic Memory: New Directions in Research

Published in print:
2002
Published Online:
March 2012
ISBN:
9780198508809
eISBN:
9780191687396
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198508809.003.0011
Subject:
Psychology, Cognitive Psychology

The question of whether any non-human species displays episodic memory is controversial. Associative accounts of animal learning recognize that behaviour can change in response to single events but ... More


Electrical stimulation of deep brain structures and speech

Elina Tripoliti and Patricia Limousin

in Speech Motor Control: New developments in basic and applied research

Published in print:
2010
Published Online:
March 2012
ISBN:
9780199235797
eISBN:
9780191696671
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235797.003.0018
Subject:
Neuroscience, Sensory and Motor Systems

This chapter describes the effects of deep brain stimulation on speech in Parkinson's disease (PD). The process involves the implantation of two electrodes either in the ventro-intermediate nucleus ... More


Cerebral Plasticity: New Perspectives

Leo M. Chalupa, Nicoletta Berardi, Matteo Caleo, Lucia Galli-Resta, and Tommaso Pizzorusso (eds)

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.001.0001
Subject:
Neuroscience, Research and Theory

The notion that neurons in the living brain can change in response to experience—a phenomenon known as “plasticity”—has become a major conceptual issue in neuroscience research as well as a practical ... More


The Plastic

Tobias Rees

in Plastic Reason: An Anthropology of Brain Science in Embryogenetic Terms

Published in print:
2016
Published Online:
January 2017
ISBN:
9780520288126
eISBN:
9780520963177
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520288126.003.0015
Subject:
Anthropology, Medical Anthropology

This concluding chapter compares the work of Alain Prochiantz and Fred Gage—both of which presented the idea that some basic embryogenetic processes might continue in adult brains. While Prochiantz ... More


Laryngeal articulatory coupling in three speech disorders

Christopher Dromey

in Speech Motor Control: New developments in basic and applied research

Published in print:
2010
Published Online:
March 2012
ISBN:
9780199235797
eISBN:
9780191696671
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235797.003.0017
Subject:
Neuroscience, Sensory and Motor Systems

This chapter focuses on data from three speech disorders to illustrate articulatory changes that arise when the larynx is the nominal target of treatment. In each case, articulatory acoustic or ... More


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