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Primary defects in lysosomal enzymes

Bryan G. Winchester

in Lysosomal Disorders of the Brain: Recent Advances in Molecular and Cellular Pathogenesis and Treatment

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198508786
eISBN:
9780191723803
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198508786.003.0004
Subject:
Neuroscience, Disorders of the Nervous System

This chapter begins with a discussion of the molecular genetics of lysosomal enzyme deficiencies. It then discusses the relation of mutations to the structure and function of lysosomal enzymes, and ... More


Genes and Human Psychological Traits

Thomas J. Jr. Bouchard

in The Innate Mind, Volume 3: Foundations and the Future

Published in print:
2008
Published Online:
January 2008
ISBN:
9780195332834
eISBN:
9780199868117
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195332834.003.0005
Subject:
Philosophy, Philosophy of Mind

This chapter shows that genetic variation is an important feature of virtually every human psychological trait and must be taken into account in any comprehensive explanation (theory) of human ... More


The Genetics of Evolutionary Novelties

Günter P. Wagner

in Homology, Genes, and Evolutionary Innovation

Published in print:
2014
Published Online:
October 2017
ISBN:
9780691156460
eISBN:
9781400851461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691156460.003.0007
Subject:
Biology, Evolutionary Biology / Genetics

This chapter examines the molecular genetics of evolutionary novelties. In particular, it investigates which molecular mechanisms might be involved in the origination of novel gene regulatory ... More


Wetware: Reaching for the brain: raking around in biological sciences

Ian J. Deary

in Looking Down on Human Intelligence: From Psychometrics to the Brain

Published in print:
2000
Published Online:
January 2008
ISBN:
9780198524175
eISBN:
9780191712531
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198524175.003.0009
Subject:
Psychology, Cognitive Psychology

This chapter describes and criticizes research that seeks the biological foundations of intelligence differences by studying head size, brain size, electroencephalographic indices, brain imaging, and ... More


Genetics of Psychological Well-Being: The role of heritability and genetics in positive psychology

Michael Pluess (ed.)

Published in print:
2015
Published Online:
August 2015
ISBN:
9780199686674
eISBN:
9780191766787
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199686674.001.0001
Subject:
Psychology, Cognitive Psychology, Evolutionary Psychology

The science of psychological well-being has gained a lot of interest in the last decade. While it has been shown that psychological well-being is partly heritable, research focused on the ... More


Techniques in physiology and genetics

Alistair Dawson

in Bird Ecology and Conservation: A Handbook of Techniques

Published in print:
2004
Published Online:
September 2007
ISBN:
9780198520863
eISBN:
9780191706189
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520863.003.0009
Subject:
Biology, Biodiversity / Conservation Biology

This chapter considers methods used to study the physiology and genetics of birds. It describes methods for obtaining samples of blood and tissue from wild birds, experimentation, anaesthesia, ... More


Studying Human Behavior: How Scientists Investigate Aggression and Sexuality

Helen E. Longino

Published in print:
2013
Published Online:
January 2014
ISBN:
9780226492872
eISBN:
9780226921822
Item type:
book
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226921822.001.0001
Subject:
Philosophy, Philosophy of Science

This book enters into the complexities of human behavioral research, a domain still dominated by the age-old debate of “nature versus nurture.” Rather than supporting one side or another or ... More


Escherichia coli

Rowland H. Davis

in The Microbial Models of Molecular Biology: From Genes to Genomes

Published in print:
2003
Published Online:
April 2010
ISBN:
9780195154368
eISBN:
9780199893935
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195154368.003.0007
Subject:
Biology, Biochemistry / Molecular Biology

This chapter focuses on the choice of a model organism, in this case the bacterium Escherichia coli, in the development of molecular genetics. It shows that this choice was made inconspicuously just ... More


Theory and Methods in Evolutionary Behavioral Genetics

Matthew C. Keller, Daniel P. Howrigan, and Matthew A. Simonson

in The Evolution of Personality and Individual Differences

Published in print:
2010
Published Online:
May 2011
ISBN:
9780195372090
eISBN:
9780199893485
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195372090.003.0010
Subject:
Psychology, Evolutionary Psychology, Social Psychology

This chapter reviews the major proximate and ultimate sources of genetic variation. It outlines the currently-available methods that can be used to examine these major sources, with an emphasis on ... More


Microbial community ecology of tick-borne human pathogens

Clay Keith, Clay Fuqua, Curt Lively, and Michael J. Wade

in Disease Ecology: Community structure and pathogen dynamics

Published in print:
2006
Published Online:
September 2007
ISBN:
9780198567080
eISBN:
9780191717871
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198567080.003.0004
Subject:
Biology, Disease Ecology / Epidemiology

The prevalence of human pathogens may be determined in part by microbial interactions within vectors. Ticks represent the primary source of vector-borne infections disease in the United States and ... More


Behaving: Its Nature and Nurture (Part 2)

Kenneth F. Schaffner

in Behaving: What's Genetic, What's Not, and Why Should We Care?

Published in print:
2016
Published Online:
May 2016
ISBN:
9780195171402
eISBN:
9780190464103
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195171402.003.0003
Subject:
Philosophy, Philosophy of Science, Moral Philosophy

This chapter focuses on recent molecular approaches to behavioral genetics including gene finding and molecular genetics. In the latter the investigators identify critical DNA variants and trace the ... More


Genetic and Environmental Influences on Positive Emotionality

Ragnhild Bang Nes

in Positive Emotion: Integrating the Light Sides and Dark Sides

Published in print:
2014
Published Online:
April 2014
ISBN:
9780199926725
eISBN:
9780199394531
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199926725.003.0009
Subject:
Psychology, Social Psychology

Some people seem to have more joy juice than others, experiencing more positive emotions. Why is this so? An abundance of studies have shown that positivity runs in families, suggesting that positive ... More


Getting Their Organ

Nathaniel Comfort

in The Science of Human Perfection: How Genes Became the Heart of American Medicine

Published in print:
2012
Published Online:
October 2013
ISBN:
9780300169911
eISBN:
9780300188875
Item type:
chapter
Publisher:
Yale University Press
DOI:
10.12987/yale/9780300169911.003.0006
Subject:
Society and Culture, Technology and Society

This chapter argues that Victor McKusik was not the founder of medical genetics, but was rather a mere guide of the discipline as it transcended into becoming molecular genetics and genomics. The ... More


Behaving: Its Nature and Nurture (Part 1)

Kenneth F. Schaffner

in Behaving: What's Genetic, What's Not, and Why Should We Care?

Published in print:
2016
Published Online:
May 2016
ISBN:
9780195171402
eISBN:
9780190464103
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195171402.003.0002
Subject:
Philosophy, Philosophy of Science, Moral Philosophy

Chapters 1 (and 2) provide a common basis and a vocabulary for appreciating the contours of behavioral and psychiatric genetics. There are three dialogues between a behavioral geneticist and an ... More


Molecular genetics of psychological well-being

Meike Bartels and Bart M. L. Baselmans

in Genetics of Psychological Well-Being: The role of heritability and genetics in positive psychology

Published in print:
2015
Published Online:
August 2015
ISBN:
9780199686674
eISBN:
9780191766787
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199686674.003.0010
Subject:
Psychology, Cognitive Psychology, Evolutionary Psychology

Psychological well-being constitutes a growing area of research in behavioral genetics. Quantitative behavioral genetic studies have revealed that a substantial part (~40%) of the variation in ... More


Genes, environment, and psychological well-being

Michael Pluess and Michael J. Meaney

in Genetics of Psychological Well-Being: The role of heritability and genetics in positive psychology

Published in print:
2015
Published Online:
August 2015
ISBN:
9780199686674
eISBN:
9780191766787
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199686674.003.0015
Subject:
Psychology, Cognitive Psychology, Evolutionary Psychology

The field of psychology has a long history of debating to what degree psychological traits are determined by genetic predispositions versus environmental factors. According to quantitative behavioral ... More


Changes in Quantitative Traits Over Time

Bruce Walsh and Michael Lynch

in Evolution and Selection of Quantitative Traits

Published in print:
2018
Published Online:
September 2018
ISBN:
9780198830870
eISBN:
9780191868986
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/oso/9780198830870.003.0001
Subject:
Biology, Evolutionary Biology / Genetics, Biochemistry / Molecular Biology

Quantitative traits—be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene—usually show ... More


Behaving: What's Genetic, What's Not, and Why Should We Care?

Kenneth F. Schaffner

Published in print:
2016
Published Online:
May 2016
ISBN:
9780195171402
eISBN:
9780190464103
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195171402.001.0001
Subject:
Philosophy, Philosophy of Science, Moral Philosophy

This book provides an overview of the recent history and methodology of behavioral genetics and psychiatric genetics. The perspective is primarily philosophical and addresses a wide range of issues, ... More


Methodology of quantitative behavior and molecular genetics

Susan C. South and Amber M. Jarnecke

in Genetics of Psychological Well-Being: The role of heritability and genetics in positive psychology

Published in print:
2015
Published Online:
August 2015
ISBN:
9780199686674
eISBN:
9780191766787
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199686674.003.0003
Subject:
Psychology, Cognitive Psychology, Evolutionary Psychology

Within the social and behavioral sciences, there is a long history of the study of genetic and environmental influences on individual differences between people. This chapter provides an overview of ... More


Introduction

in Genomes and What to Make of Them

Published in print:
2008
Published Online:
March 2013
ISBN:
9780226172958
eISBN:
9780226172965
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226172965.003.0001
Subject:
Philosophy, Philosophy of Science

This introductory chapter first sets out the book's main purpose, which is to convey some sense of the new powers with which we are being endowed as genomics and a new molecular genetics grow out of ... More


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