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Statistics and Informatics in Molecular Cancer Research

Carsten Wiuf and Claus L. Andersen (eds)

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199532872
eISBN:
9780191714467
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199532872.001.0001
Subject:
Mathematics, Probability / Statistics, Biostatistics

This book discusses novel advances in informatics and statistics in molecular cancer research. Through eight chapters it discusses specific topics in cancer research, talks about how the topics give ... More


Analysis of DNA methylation in cancer

Fabian Model, Jörn Lewin, Catherine Lofton-Day, and Gunter Weiss

in Statistics and Informatics in Molecular Cancer Research

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199532872
eISBN:
9780191714467
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199532872.003.0005
Subject:
Mathematics, Probability / Statistics, Biostatistics

This chapter gives an overview of algorithms and statistical methods used for measuring and analyzing DNA methylation in cancer research. It starts with a short introduction into the biology of DNA ... More


The Ageing Hippocampus

Lan T. Hoang, James P. Lister, and Carol A. Barnes

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0009
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

This chapter reviews alterations observed in the hippocampus during normative ageing in the absence of pathology. Topics include discussions of age-related spatial memory deficits across mammalian ... More


Mercury Cycling in Terrestrial Watersheds

James B. Shanley and Kevin Bishop

in Mercury in the Environment: Pattern and Process

Published in print:
2012
Published Online:
September 2012
ISBN:
9780520271630
eISBN:
9780520951396
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520271630.003.0008
Subject:
Biology, Ecology

This chapter discusses mercury cycling in the terrestrial landscape, including inputs from the atmosphere, accumulation in soils and vegetation, outputs in streamflow and volatilization, and effects ... More


Mercury Hotspots in Freshwater Ecosystems: Drivers, Processes, and Patterns

Celia Y. Chen, Charles T. Driscoll, and Neil C. Kamman

in Mercury in the Environment: Pattern and Process

Published in print:
2012
Published Online:
September 2012
ISBN:
9780520271630
eISBN:
9780520951396
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520271630.003.0009
Subject:
Biology, Ecology

Studies conducted in a wide range of freshwater ecosystems have revealed specific suites of attributes that predispose certain ecosystems to being sites of elevated MeHg bioaccumulation in fish and ... More


Mercury in the Marine Environment

Frank J. Black, Christopher H. Conaway, and A. Russell Flegal

in Mercury in the Environment: Pattern and Process

Published in print:
2012
Published Online:
September 2012
ISBN:
9780520271630
eISBN:
9780520951396
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520271630.003.0010
Subject:
Biology, Ecology

The study of mercury in marine ecosystems is necessary to understand and minimize the chronic, sublethal toxicity due to exposure to organomercury in the marine environment and resources. The ... More


Epigenetic influences on mental illness over the life course

Monica Uddin and Levent Sipahi

in A Life Course Approach to Mental Disorders

Published in print:
2013
Published Online:
January 2014
ISBN:
9780199657018
eISBN:
9780191748097
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199657018.003.0022
Subject:
Public Health and Epidemiology, Public Health

Lifetime experiences have long been recognized as important determinants of mental health and illness; however, the biological mechanisms through which social exposures influence mental health, and ... More


A Statistical Framework for Mediation in Environmental Epigenetics

Duncan C. Thomas

in Statistical Approaches to Gene X Environment Interactions for Complex Phenotypes

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262034685
eISBN:
9780262335522
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262034685.003.0011
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

The biological effects of genes depend upon how they are expressed in target tissues at various points in time, which is determined by their epigenetic state and in turn may be influenced by the ... More


Genetics and epigenetics of parental care

Frances A. Champagne and James P. Curley

in The Evolution of Parental Care

Published in print:
2012
Published Online:
December 2013
ISBN:
9780199692576
eISBN:
9780191774737
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199692576.003.0017
Subject:
Biology, Evolutionary Biology / Genetics

This chapter describes how both genetic and epigenetic approaches have been applied to the study of parental care/caregiving, with a particular focus on species in which there have been molecular ... More


Bayesian Networks in the Study of Genome-wide DNA Methylation

Meromit Singer and Lior Pachter

in Probabilistic Graphical Models for Genetics, Genomics, and Postgenomics

Published in print:
2014
Published Online:
December 2014
ISBN:
9780198709022
eISBN:
9780191779619
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198709022.003.0014
Subject:
Mathematics, Probability / Statistics, Biostatistics

This chapter explores the use of Bayesian networks in the study of genome-scale deoxyribonucleic acid (DNA) methylation. It begins by describing different experimental methods for the genome-scale ... More


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