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Evolution, developmental plasticity, and metabolic disease

Christopher W. Kuzawa, Peter D. Gluckman, Mark A. Hanson, and Alan S. Beedle

in Evolution in Health and Disease

Published in print:
2007
Published Online:
April 2010
ISBN:
9780199207466
eISBN:
9780191728167
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199207466.003.0019
Subject:
Biology, Evolutionary Biology / Genetics

Early-life events influence late life health. An adverse early environment changes the developing organism's metabolism, physiology, and organ structure to increase risk of adult metabolic disorders, ... More


Developmental Origins of Obesity

Frank B. Hu

in Obesity Epidemiology

Published in print:
2008
Published Online:
September 2009
ISBN:
9780195312911
eISBN:
9780199865260
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195312911.003.0019
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

This chapter focuses on pre- and perinatal factors that determine obesity and its consequences later on in life. Topics discussed include measurement of obesity in young children, developmental ... More


Family-based studies applied to the influence of early life factors on cardiovascular disease

Debbie A Lawlor and David A Leon

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0013
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

There is good evidence that associations exist between fetal and other early life factors and subsequent risk of cardiovascular disease (CVD) that can be replicated in a range of settings. These ... More


* The developmental origins of well-being

David J.P. Barker

in The Science of Well-Being

Published in print:
2005
Published Online:
March 2012
ISBN:
9780198567523
eISBN:
9780191693670
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198567523.003.0003
Subject:
Psychology, Cognitive Psychology

The first part of this chapter discusses the developmental origins hypothesis, and the ‘life history theory’ and its biological implications regarding diseases such as heart disease, diabetes, ... More


Theoretical underpinning for the use of intergenerational studies in life course epidemiology

Debbie A Lawlor, Sam Leary, and George Davey Smith

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0002
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Intergenerational studies have been widely used in life course epidemiology both to examine primary research hypotheses and to explore underlying mechanisms for established associations. This chapter ... More


Contemporary Mainstream Epidemiologic Theory: Biomedical and Lifestyle

Nancy Krieger

in Epidemiology and the People’s Health: Theory and Context

Published in print:
2011
Published Online:
May 2011
ISBN:
9780195383874
eISBN:
9780199893607
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195383874.003.0005
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

Chapter 5 critically analyzes the biomedical and lifestyle approaches dominating epidemiologic theorizing and research since the mid-20th century. Tracing the origins of the term “biomedicine,” it ... More


Discussant chapter—using family-based designs in life course epidemiology

John Lynch and Seungmi Yang

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0016
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The three chapters in this section offer different but complementary conceptualizations of ‘family’. Morton and Rich Edwards used ‘family’ to document inter-generational concordance of reproductive ... More


Theoretical underpinning for the use of twin studies in life course epidemiology

Ruth J F Loos, Charlotte L Ridgway, and Ken K Ong

in Family matters: Designing, analysing and understanding family based studies in life course epidemiology

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199231034
eISBN:
9780191723841
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199231034.003.0004
Subject:
Public Health and Epidemiology, Public Health, Epidemiology

The classical twin design is used in genetic epidemiology to estimate the heritability of a trait or disease. Despite potential biases for certain traits at specific stages during the life course, ... More


Blinded by Science: The Social Implications of Epigenetics and Neuroscience

David Wastell and Susan White

Published in print:
2017
Published Online:
September 2017
ISBN:
9781447322337
eISBN:
9781447322351
Item type:
book
Publisher:
Policy Press
DOI:
10.1332/policypress/9781447322337.001.0001
Subject:
Political Science, Public Policy

In recent years, new areas of biology, especially epigenetics and neuroscience, have enthralled the public imagination. They have been used as powerful arguments for developing social policy in a ... More


Cancers, Brain Disorders, and the Feminization of Boys: Can We Avoid Poisoning Our Children?

Carl F. Cranor

in Tragic Failures: How and Why We are Harmed by Toxic Chemicals

Published in print:
2017
Published Online:
February 2017
ISBN:
9780190635756
eISBN:
9780190635787
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780190635756.003.0003
Subject:
Philosophy, Moral Philosophy, General

Infectious diseases in the United States have declined while noninfectious diseases due to environmental factors or gene-environment interactions are increasing. Many noninfectious diseases, recently ... More


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