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Neuropathology of Aging

Dara L. Dickstein, John H. Morrison, and Patrick R. Hof

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0003
Subject:
Neuroscience, Techniques, Development

Alzheimer's disease (AD) is characterized by extensive, yet selective, neuron death in the cerebral neocortex leading to dramatic decline in cognitive abilities and memory. A more modest disruption ... More


Molecular determinants of dendrite and spine development

Franck Polleux and Anirvan Ghosh

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems

Information processing in neurons is critically dependent on dendritic morphology. The overall extent and orientation of dendrites determines the kinds of input a neuron receives. Fine dendritic ... More


Functional plasticity at dendritic synapses

Zachary F. Mainen and Larry F. Abbott

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0018
Subject:
Neuroscience, Molecular and Cellular Systems

Most synapses are made onto dendrites, and most excitatory connections are made onto dendritic spines. Synaptic plasticity is thus an intrinsically dendritic phenomenon, but the functional ... More


Biochemical compartmentalization in dendrites

Fritjof Helmchen and U. Valentin Nägerl

in Dendrites

Published in print:
2016
Published Online:
May 2016
ISBN:
9780198745273
eISBN:
9780191819735
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198745273.003.0010
Subject:
Neuroscience, Sensory and Motor Systems, Molecular and Cellular Systems

Dendrites have both an electrical and a biochemical character, which are closely linked. This chapter discusses dendritic structures as compartments for chemical signals such as concentration changes ... More


A Thorny Question: The Role of Spine Morphogenesis in Adaptive Plasticity

Hamilton Andrew and Zito Karen

in Cerebral Plasticity: New Perspectives

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.003.0011
Subject:
Neuroscience, Research and Theory

This chapter discusses some of the most exciting recent discoveries concerning the mechanisms of spine synapse plasticity and reviews the most intriguing questions which still loom over these tiny ... More


Evolution and scaling of dendrites

Samuel S.-H. Wang, Anthony E. Ambrosini, and Gayle M. Wittenberg

in Dendrites

Published in print:
2016
Published Online:
May 2016
ISBN:
9780198745273
eISBN:
9780191819735
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198745273.003.0002
Subject:
Neuroscience, Sensory and Motor Systems, Molecular and Cellular Systems

Dendrites, the neuronal processes that receive synaptic inputs, are found in all nervous systems. The great diversity of dendrites, both within individual species and across phylogeny, reflects their ... More


The Synaptic Organization of the Brain

Gordon M. Shepherd (ed.)

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195159561
eISBN:
9780199864447
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195159561.001.1
Subject:
Neuroscience, Molecular and Cellular Systems, Development

Synapses are the contact sites that enable neurons to form connections between each other in order to transmit and process neural information. Synaptic organization is concerned with the principles ... More


Introduction

Rafael Yuste

in Dendritic Spines

Published in print:
2010
Published Online:
August 2013
ISBN:
9780262013505
eISBN:
9780262259286
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013505.003.0001
Subject:
Neuroscience, Research and Theory

This chapter aims to integrate all current knowledge on dendritic spines, and provide information on the important features of the circuits in which they operate. It discusses the various aspects of ... More


Dendritic Spines

Rafael Yuste

Published in print:
2010
Published Online:
August 2013
ISBN:
9780262013505
eISBN:
9780262259286
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013505.001.0001
Subject:
Neuroscience, Research and Theory

Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But a hundred and twenty years after spines were first ... More


Discovery

Rafael Yuste

in Dendritic Spines

Published in print:
2010
Published Online:
August 2013
ISBN:
9780262013505
eISBN:
9780262259286
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013505.003.0002
Subject:
Neuroscience, Research and Theory

This chapter narrates the discovery of dendritic spines. It begins with Santiago Ramón y Cajal, a Spanish professor of Pathology and Histology, and his work entitled Estractura delos centros ... More


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