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Real People: Personal Identity without Thought Experiments

Kathleen V. Wilkes

Published in print:
1993
Published Online:
October 2011
ISBN:
9780198240808
eISBN:
9780191680281
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198240808.001.0001
Subject:
Philosophy, Philosophy of Mind, Metaphysics/Epistemology

This book explores the scope and limits of the concept of a person — a vexed question in contemporary philosophy. The author begins by questioning the methodology of thought-experimentation, arguing ... More


The Alzheimer Conundrum: Entanglements of Dementia and Aging

Margaret Lock

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
book
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.001.0001
Subject:
Anthropology, Social and Cultural Anthropology

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no ... More


MRI and the Differential Diagnosis of Dementia

António J. Bastos-Leite and Philip Scheltens

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0016
Subject:
Neuroscience, Techniques, Development

Magnetic resonance imaging (MRI) has opened up the way to diagnose dementia in vivo. It provides clear evidence for hippocampal atrophy in Alzheimer's disease (AD), lobar atrophy in frontotemporal ... More


Making and Remaking Alzheimer Disease

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0002
Subject:
Anthropology, Social and Cultural Anthropology

This chapter focuses on the “discovery” of Alzheimer disease (AD) and a somewhat condensed genealogy of its history to the present time. Emphasis is given to the virtual disappearance of AD for over ... More


Afterword: Portraits from the Mind

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0011
Subject:
Anthropology, Social and Cultural Anthropology

This concluding chapter presents emerging knowledge in both epigenetics and epidemiology, suggesting that forms of prevention that take a public health approach, including lifestyle changes, reduced ... More


Imaging the Aging Brain

William Jagust and Mark D'Esposito (eds)

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.001.0001
Subject:
Neuroscience, Techniques, Development

The study of brain aging has been revolutionized through advances in molecular neuroscience, cognitive neuroscience, and brain imaging. The application of new concepts and techniques has permitted ... More


Palliative Care for Non-cancer Patients

Julia Addington-Hall and Irene Higginson (eds)

Published in print:
2001
Published Online:
November 2011
ISBN:
9780192629609
eISBN:
9780191730054
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780192629609.001.0001
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making

The specialty of palliative care has traditionally grown out of oncology and there has been little research into the needs of patients dying from causes other than cancer. Few non-cancer patients ... More


Developmental Influences on Adult Intelligence: The Seattle longitudinal study

K. Warner Schaie

Published in print:
2005
Published Online:
September 2007
ISBN:
9780195156737
eISBN:
9780199786817
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195156737.001.0001
Subject:
Psychology, Developmental Psychology

This book lays out the reasons why we should study cognitive development in adulthood, and presents the history, latest data, and results from the Seattle Longitudinal Study (SLS), which now extends ... More


Cognitive Event-Related Studies

Jay A. Liveson and Dong M. Ma

in Laboratory Reference for Clinical Neurophysiology

Published in print:
1999
Published Online:
March 2012
ISBN:
9780195129243
eISBN:
9780199847792
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195129243.003.0016
Subject:
Neuroscience, Techniques

P300 potentials are slow waves that depend on stimuli containing information that the subject must process. The types of stimuli are independent of the sensory modality of the stimuli, and have ... More


Imaging Cognitive Decline in Aging: Predicting Decline with Structural Imaging

Jeffrey Kaye

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0010
Subject:
Neuroscience, Techniques, Development

The focus of this chapter is predicting cognitive decline or dementia in normal older people using structural imaging. Key questions addressed include the following: What are the major methods, both ... More


Differential Diagnosis of Dementia Using Functional Neuroimaging

Eric Salmon, Fabienne Collette, and Gaëtan Garraux

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0015
Subject:
Neuroscience, Techniques, Development

Functional neuroimaging in neurodegenerative dementias provides 3D representations of brain activity that are relatively characteristic of the underlying phenotypic distribution of cerebral lesions. ... More


The Role of Longitudinal Studies in the Early Detection of Dementia

K. Warner Schaie

in Developmental Influences on Adult Intelligence: The Seattle longitudinal study

Published in print:
2005
Published Online:
September 2007
ISBN:
9780195156737
eISBN:
9780199786817
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195156737.003.0017
Subject:
Psychology, Developmental Psychology

Although the Seattle Longitudinal Study was designed to focus on cognitive changes in normal community-dwelling populations, it is inevitable that a prospective study of aging will eventually include ... More


Continuity in the Conceptual System: Acquisition, Breakdown, and Reorganization

Jean Matter Mandler

in Foundations of Mind: Origins of Conceptual Thought

Published in print:
2007
Published Online:
September 2007
ISBN:
9780195311839
eISBN:
9780199786770
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195311839.003.0009
Subject:
Psychology, Developmental Psychology

This chapter summarizes the large body of data on the initial organization of the conceptual system. The initial, and perhaps most important, conclusion that can be drawn from the data is that ... More


The Role of Neuroimaging Biomarkers in Personalized Medicine for Neurodegenerative and Psychiatric Disorders

Ellen M. Migo, Steve C.R. Williams, William R. Crum, Matthew J. Kempton, and Ulrich Ettinger

in Integrative Neuroscience and Personalized Medicine

Published in print:
2010
Published Online:
January 2011
ISBN:
9780195393804
eISBN:
9780199863495
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195393804.003.0008
Subject:
Neuroscience, Disorders of the Nervous System

There is a clear need for biomarkers in neuro-degenerative and psychiatric disorders for both early and differential diagnosis, personalized prediction of treatment response, and in drug discovery. ... More


Mental and behavioural disorders

Fabrizio Benedetti

in Placebo Effects: Understanding the mechanisms in health and disease

Published in print:
2008
Published Online:
September 2009
ISBN:
9780199559121
eISBN:
9780191724022
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199559121.003.0005
Subject:
Neuroscience, Molecular and Cellular Systems

In depression, a fluoxetine treatment and a placebo treatment affect similar brain regions. In addition, covert (unexpected) administration of anti-anxiety drugs is less effective than overt ... More


Living with Alzheimer's: Managing Memory Loss, Identity, and Illness

Renée L. Beard

Published in print:
2016
Published Online:
January 2017
ISBN:
9781479800117
eISBN:
9781479855377
Item type:
book
Publisher:
NYU Press
DOI:
10.18574/nyu/9781479800117.001.0001
Subject:
Social Work, Health and Mental Health

Alzheimer’s is ubiquitous. Stories of the heart-wrenching drudgery of care giving, escalating incidence rates, and the new path to a cure just around the corner are everywhere. Yet we rarely see or ... More


Neuropsychological assessment of the orbitofrontal cortex

David H. Zald

in The Orbitofrontal Cortex

Published in print:
2006
Published Online:
February 2010
ISBN:
9780198565741
eISBN:
9780191723971
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198565741.003.0018
Subject:
Neuroscience, Behavioral Neuroscience

This chapter reviews the neuropsychological assessment of orbitofrontal functions. It starts by describing the major categories of neurological disorders that result in lesions of the orbitofrontal ... More


Frontotemporal dementia and the orbitofrontal cortex

Po H. Lu, Negar Khanlou, and Jeffrey L. Cummings

in The Orbitofrontal Cortex

Published in print:
2006
Published Online:
February 2010
ISBN:
9780198565741
eISBN:
9780191723971
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198565741.003.0024
Subject:
Neuroscience, Behavioral Neuroscience

Patients with frontotemporal dementia (FTD) manifest severe behavioral and personality alterations associated with orbitofrontal cortex (OFC) dysfunction. This chapter provides a review of the ... More


Normal and Pathological Cognitive Aging in Late Adulthood

Timothy A. Salthouse

in Major Issues in Cognitive Aging

Published in print:
2009
Published Online:
May 2010
ISBN:
9780195372151
eISBN:
9780199776948
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195372151.003.0005
Subject:
Psychology, Cognitive Neuroscience, Cognitive Psychology

This chapter focuses on cognitive functioning in late adulthood. It discusses three related topics: dementia, the preclinical phase of dementia, and the risk factors for cognitive decline and ... More


Communicating with people with dementia

Kate Allan and John Killick

in Supportive care for the person with dementia

Published in print:
2009
Published Online:
November 2011
ISBN:
9780199554133
eISBN:
9780191730269
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199554133.003.0023
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter argues that communication should be central to how we think about dementia and how we work with those who live with it. As for the emerging concept of ‘supportive care’ for people with ... More


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