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Aperiodic Crystals: From Modulated Phases to Quasicrystals

Ted Janssen, Gervais Chapuis, and Marc de Boissieu

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198567776
eISBN:
9780191718335
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198567776.001.0001
Subject:
Physics, Crystallography

Until the 1970s, all materials studied consisted of periodic arrays of unit cells, or were amorphous. In the last decades a new class of solid state matter, called aperiodic crystals, has been found. ... More


Crystals, X-rays and Proteins: Comprehensive Protein Crystallography

Dennis Sherwood and Jon Cooper

Published in print:
2010
Published Online:
January 2011
ISBN:
9780199559046
eISBN:
9780191595028
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199559046.001.0001
Subject:
Physics, Crystallography

This book presents a complete account of the theory of the diffraction of X-rays by crystals with particular reference to the processes of determining the structures of protein molecules. The book ... More


Crystal Structure Analysis: Principles and Practice

William Clegg, Alexander J Blake, Jacqueline M Cole, John S O Evans, Peter Main, Simon Parsons, and David J Watkin (eds)

Published in print:
2009
Published Online:
September 2009
ISBN:
9780199219469
eISBN:
9780191722516
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199219469.001.0001
Subject:
Physics, Crystallography

This book presents a less mathematical approach to X-ray crystal structure determination than is given in some detailed texts and concentrates on practical aspects. The book provides the necessary ... More


Conclusions

GAUTAM R. DESIRAJU and THOMAS STEINER

in The Weak Hydrogen Bond: In Structural Chemistry and Biology

Published in print:
2001
Published Online:
January 2010
ISBN:
9780198509707
eISBN:
9780191708206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509707.003.0006
Subject:
Physics, Crystallography

The weak hydrogen bond was first identified in 1935, but it was only in the early 1990s that it really permeated into the consciousness of chemists and biologists. It only seems natural that this ... More


Max Perutz and the SPSL

Georgina Ferry

in In Defence of Learning: The Plight, Persecution, and Placement of Academic Refugees, 1933-1980s

Published in print:
2011
Published Online:
January 2013
ISBN:
9780197264812
eISBN:
9780191754029
Item type:
chapter
Publisher:
British Academy
DOI:
10.5871/bacad/9780197264812.003.0006
Subject:
Sociology, Migration Studies (including Refugee Studies)

This chapter focuses on Austrian-born molecular biologist Max Perutz (1914–2002). Perutz was one of twenty scientific refugees from continental Europe who went on to win Nobel Prizes. A chemist and ... More


Applications of the Pilot ACE and the DEUCE

Tom Vickers

in Alan Turing's Automatic Computing Engine: The Master Codebreaker's Struggle to build the Modern Computer

Published in print:
2005
Published Online:
January 2008
ISBN:
9780198565932
eISBN:
9780191714016
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198565932.003.0013
Subject:
Mathematics, History of Mathematics

This chapter discusses applications of the Pilot ACE. These applications include linear equations, photogrammetry, traffic simulation, matrix programmes, demonstration programmes, and ... More


In-house macromolecular data collection

Mark R. Sanderson

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0005
Subject:
Biology, Biochemistry / Molecular Biology

In the field of macromolecular crystallography, a renaissance occurred in data collection with the advent of two-dimensional area detectors. These rapidly superseded film cameras and diffractometers ... More


Solving the phase problem using isomorphous replacement

Sherin S. Abdel-Meguid

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0006
Subject:
Biology, Biochemistry / Molecular Biology

This chapter begins with a discussion of the theoretical basis of isomorphous replacement. It then discusses the selection of heavy-atom reagents, heavy atoms and their ligands, preparation of ... More


Getting a macromolecular model: model building, refinement, and validation

R. J. Morris, A. Perrakis, and V. S. Lamzin

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0011
Subject:
Biology, Biochemistry / Molecular Biology

This chapter casts the high-throughput automation efforts being developed to meet the needs of Structural Genomics initiatives in the framework of an optimization problem. It gives a general overview ... More


RNA crystallogenesis

Benoît Masquida, Boris François, Andreas Werner, and Eric Westhof

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0014
Subject:
Biology, Biochemistry / Molecular Biology

The number of RNA crystal structures has increased in an exponential manner mainly due to the fact that RNA is increasingly viewed as a predominant part of biological processes such as translation, ... More


Crystallography in the study of protein–DNA interaction

Maninder K. Sohi and Ivan Laponogov

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0015
Subject:
Biology, Biochemistry / Molecular Biology

In the living cell, protein-DNA interactions take place during genetic processes such as chromatin organization, recombination, replication, transcription, and DNA repair. In order to fully ... More


Virus crystallography

Elizabeth E. Fry, Nicola G. A. Abrescia, and David I. Stuart

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0016
Subject:
Biology, Biochemistry / Molecular Biology

This chapter discusses all aspects of the methodology used to solve isometric virus structures with separate case study examples for two demanding examples, the blue tongue virus core (BTV) and ... More


Macromolecular crystallography in drug design

Sherin S. Abdel-Meguid

in Macromolecular Crystallography: conventional and high-throughput methods

Published in print:
2007
Published Online:
September 2007
ISBN:
9780198520979
eISBN:
9780191706295
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198520979.003.0017
Subject:
Biology, Biochemistry / Molecular Biology

This chapter discusses macromolecular crystallography in drug discovery. Currently, all large and most small pharmaceutical and biotechnology companies have invested in macromolecular ... More


Conceiving a Master Molecule

Jan Sapp

in Genesis: The Evolution of Biology

Published in print:
2003
Published Online:
September 2007
ISBN:
9780195156195
eISBN:
9780199790340
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195156195.003.0016
Subject:
Biology, Evolutionary Biology / Genetics

This chapter focuses on the discovery of DNA. The discovery of DNA as the basis of the gene, how it is reproduced, and how it affects protein synthesis was the pinnacle of life sciences in the 20th ... More


Michael Polanyi: Scientist and Philosopher

William Taussig Scott and Martin X. Moleski

Published in print:
2005
Published Online:
July 2005
ISBN:
9780195174335
eISBN:
9780199835706
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/019517433X.001.0001
Subject:
Religion, Philosophy of Religion

Michael Polanyi (1891–1976) was born to a Viennese family living in Hungary. After obtaining a medical degree, he served in the Austro-Hungarian army in World War I, then chose Austrian citizenship ... More


Electron crystallography ‐ an introduction

Xiaodong Zou, Sven Hovmöller, and Peter Oleynikov

in Electron Crystallography: Electron Microscopy and Electron Diffraction

Published in print:
2011
Published Online:
January 2012
ISBN:
9780199580200
eISBN:
9780191731211
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199580200.003.0001
Subject:
Physics, Crystallography

The historical introduction covers the parallel developments in EM on inorganic and biological samples. Vainshtein, Pinsker and Zvyagin in Moscow solved structures from electron-diffraction patterns ... More


Introduction

Joachim Frank

in Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State

Published in print:
2006
Published Online:
April 2010
ISBN:
9780195182187
eISBN:
9780199893416
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195182187.003.0001
Subject:
Biology, Biochemistry / Molecular Biology

This introductory chapter begins with an appreciation of the unique position of electron microscopy in biological research as it bridges a wide gap between X-ray crystallography and light microscopy. ... More


 The Fiber Institute: 1920–1923

William Taussig Scott and Martin X. Moleski

in Michael Polanyi: Scientist and Philosopher

Published in print:
2005
Published Online:
July 2005
ISBN:
9780195174335
eISBN:
9780199835706
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/019517433X.003.0004
Subject:
Religion, Philosophy of Religion

Fritz Haber hired Polanyi to work in the Fiber Chemistry Group of the Kaiser Wilhelm Institute in Berlin. Polanyi helped develop the rotating-crystal method of X-ray crystallography, made solid ... More


William and Lawrence Bragg, Father and Son: The Most Extraordinary Collaboration in Science

John Jenkin

Published in print:
2007
Published Online:
January 2008
ISBN:
9780199235209
eISBN:
9780191715631
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235209.001.0001
Subject:
Physics, History of Physics

This book describes how Lawrence and William Bragg, son and father, invented, developed, and led the scientific field of X-ray crystallography for fifty years, transforming much of modern science. ... More


Crystallography of Modular Materials

Giovanni Ferraris, Emil Makovicky, and Stefano Merlino

Published in print:
2008
Published Online:
September 2008
ISBN:
9780199545698
eISBN:
9780191712111
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199545698.001.0001
Subject:
Physics, Crystallography

This book provides a treatment of theories and applications in the rapidly expanding field of the crystallography of modular materials. Molecules are the natural modules from which molecular ... More


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