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Imaging Cognitive Decline in Aging: Predicting Decline with Structural Imaging

Jeffrey Kaye

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0010
Subject:
Neuroscience, Techniques, Development

The focus of this chapter is predicting cognitive decline or dementia in normal older people using structural imaging. Key questions addressed include the following: What are the major methods, both ... More


Structural Imaging of Mild Cognitive Impairment

Clifford R. Jack

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0012
Subject:
Neuroscience, Techniques, Development

This chapter describes the concept of mild cognitive impairment (MCI), the initial construct of amnestic MCI as well as the expanded construct that includes both amnestic and nonamnestic forms. The ... More


Effects of epileptiform EEG discharges on cognitive function

Albert P. Aldenkamp

in Epilepsy and Memory

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199580286
eISBN:
9780191739408
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199580286.003.0009
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

This chapter reviews the evidence on the cognitive impact of interictal epileptiform electroencephalogram (EEG) discharges. Such cognitive impairment has a direct or more remote relation to episodes ... More


Amyloid Imaging and (What is “Normal”?) Aging

William E. Klunk and Chester A. Mathis

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0014
Subject:
Neuroscience, Techniques, Development

One thing that has become clear from amyloid imaging studies is how early the full burden of plaques accumulate, often by the time a patient first develops symptoms. This finding brings with it the ... More


Paths to Alzheimer Prevention

Margaret Lock

in The Alzheimer Conundrum: Entanglements of Dementia and Aging

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.003.0004
Subject:
Anthropology, Social and Cultural Anthropology

This chapter looks at the adoption in the 1980s of the clinical diagnosis known as “mild cognitive impairment” (MCI). Formal recognition of MCI, the value of which continues to be debated in some ... More


Alzheimer’s Disease

Maija Pihlajamäki and Hilkka Soininen

in The Clinical Neurobiology of the Hippocampus: An integrative view

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199592388
eISBN:
9780199949922
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199592388.003.0012
Subject:
Neuroscience, Disorders of the Nervous System, Behavioral Neuroscience

The clinical spectrum of hippocampal dysfunction encompasses a wide range of neuropsychiatric symptoms. The present chapter aims at addressing the hippocampal involvement in the most common form of ... More


The Early Detection of Alzheimer's Disease with Positron Emission Tomography

Rachel Mistur, Lisa Mosconi, Remigiusz Switalski, Susan De Santi, Yi Li, Lidia Glodzik, Miroslaw Brys, Wai Tsui, Henry Rusinek, and Mony J. de Leon

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0011
Subject:
Neuroscience, Techniques, Development

Reductions in the cerebral metabolic rate of glucose (CMRglc), a measure of neuronal function, have proven to be a promising tool in the early diagnosis of Alzheimer's disease (AD). FDG-PET imaging ... More


Cognitive Impairment

Giuseppe Zuccalà, Alice Laudisio, and Roberto Bernabei

in Supportive Care in Heart Failure

Published in print:
2008
Published Online:
November 2011
ISBN:
9780198570288
eISBN:
9780191730030
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198570288.003.0014
Subject:
Palliative Care, Patient Care and End-of-Life Decision Making, Pain Management and Palliative Pharmacology

This chapter starts by addressing the epidemiology and aetiology of heart failure (HF) with cognitive impairment. The clinical features and treatment of cognitive impairment associated with HF are ... More


Vascular cognitive impairment

John Bowler

in Cognitive Neurology: A clinical textbook

Published in print:
2008
Published Online:
March 2012
ISBN:
9780198569275
eISBN:
9780191724213
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198569275.003.0014
Subject:
Neuroscience, Techniques

Vascular cognitive impairment (VCI) is a relatively new term intended to encompass and replace the older concept of vascular dementia (VaD). Put simply, VCI refers to cognitive impairment of any ... More


NEURODEVELOPMENTAL MECHANISMS IN CHILDHOOD PSYCHOPATHOLOGY: THE EXAMPLE OF ABNORMAL SOCIAL ORIENTING IN AUTISM

Noah J. Sasson, Lauren Turner Brown, and Joseph Piven

in Cognitive Neuroscience, Development, and Psychopathology: Typical and Atypical Developmental Trajectories of Attention

Published in print:
2012
Published Online:
September 2012
ISBN:
9780195315455
eISBN:
9780199979066
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195315455.003.0011
Subject:
Psychology, Cognitive Psychology, Developmental Psychology

Individuals with autism demonstrate marked impairments in the perception, processing, and interpretation of social information. Recent findings suggest that abnormal social orienting may serve as a ... More


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