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NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

W. Otto Friesen and Jonathon Friesen

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.001.0001
Subject:
Psychology, Cognitive Neuroscience

The electrical membrane potential is an important property for the functioning of living cells. Temporal variations of this potential generated by synaptic interactions and expressed as nerve ... More


Axon Models

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0011
Subject:
Psychology, Cognitive Neuroscience

The Axon model simulates the equations and parameters derived from experiments by Hodgkin and Huxley on the squid giant axon. Because of the exact correspondence between the equations incorporated ... More


Equations Underlying the Patch Model

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0017
Subject:
Psychology, Cognitive Neuroscience

The Patch model illustrates results obtained from patch-clamp experiments. This chapter describes the elementary equations for currents through individual ion channels, based on Ohm's law. Because ... More


Equations Underlying the Axon Models

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0019
Subject:
Psychology, Cognitive Neuroscience

The Axon models present the fundamental concepts that underlie the generation and propagation of the nerve impulses. This chapter includes a complete list of the equations that describe the ... More


Patch Model

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0009
Subject:
Psychology, Cognitive Neuroscience

The Patch model simulates the dynamics of a small piece of cell membrane as observed with the patch-clamp technique. Either individual channels in a small patch of membrane or the macroscopic current ... More


Accurate Clock Pendulums

Robert J. Matthys

Published in print:
2004
Published Online:
January 2010
ISBN:
9780198529712
eISBN:
9780191712791
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198529712.001.0001
Subject:
Physics, History of Physics

The Shortt clock, made in the 1920s, is the most famous accurate clock pendulum ever known, having an accuracy of one second per year when kept at nearly constant temperature. Almost all of a ... More


Basis of the Nerve Impulse

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0004
Subject:
Psychology, Cognitive Neuroscience

The rapid conduction of signals by neurons over distances greater than about 1 mm occurs almost exclusively by electrical impulses. This chapter presents the fundamental concepts that underlie the ... More


Synaptic ‘Noise’: Experiments, Computational Consequences and Methods to Analyse Experimental Data

Alain Destexhe and Michelle Rudolph-Lilith

in Stochastic Methods in Neuroscience

Published in print:
2009
Published Online:
February 2010
ISBN:
9780199235070
eISBN:
9780191715778
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235070.003.0009
Subject:
Mathematics, Biostatistics

In the cerebral cortex of awake animals, neurons are subject to tremendous fluctuating activity, mostly of synaptic origin, termed “synaptic noise”. Synaptic noise is the dominant source of membrane ... More


Patch-Clamp Recording

W. Otto Friesen and Jonathon A. Friesen

in NeuroDynamix II: Concepts of Neurophysiology Illustrated by Computer Simulations

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195371833
eISBN:
9780199865178
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195371833.003.0002
Subject:
Psychology, Cognitive Neuroscience

Invented by Bert Sakmann and Erwin Neher during the 1970s, the patch-clamp recording technique aids scientists in examining the functions of individual protein molecules that form ion channels in ... More


Voltage-clamp studies in axons: Macroscopic and single-channel currents

WERNER VOGEL and JÜRGEN R. SCHWARZ

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0013
Subject:
Neuroscience, Disorders of the Nervous System

This chapter describes macroscopic membrane currents measured in amphibian and mammalian nodes of Ranvier with the voltage-clamp method. These results are compared with those of single-channel ... More


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