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Markov Chain Models of Ion Channels and Calcium Release Sites

Jeffrey R. Groff, Hilary DeRemigio, and Gregory D. Smith

in Stochastic Methods in Neuroscience

Published in print:
2009
Published Online:
February 2010
ISBN:
9780199235070
eISBN:
9780191715778
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199235070.003.0002
Subject:
Mathematics, Biostatistics

This chapter is an introduction to modelling stochastically gating ion channels using continuous-time discrete-state Markov chains. Analytical and numerical methods are presented for determining ... More


The Axon: Structure, Function and Pathophysiology

Stephen G. Waxman, Jeffery D. Kocsis, and Peter K. Stys (eds)

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.001.0001
Subject:
Neuroscience, Disorders of the Nervous System

The axon, which is interposed between the cell body and the synaptic terminals in most neurons, plays a crucial role in connecting neurons and acting as a conduit for the transmission of information ... More


Synapse-to-nucleus calcium signalling

Giles E. Hardingham

in Molecular Biology of the Neuron

Published in print:
2004
Published Online:
September 2009
ISBN:
9780198509981
eISBN:
9780191723810
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198509981.003.0010
Subject:
Neuroscience, Molecular and Cellular Systems

Many extracellular stimuli result in an elevation of intracellular calcium concentration. Calcium ions act as messengers, coupling many external events or stimuli to the cell's responses to those ... More


Neuromuscular transmission

Daniel Kernell

in The Motoneurone and its Muscle Fibres

Published in print:
2006
Published Online:
September 2009
ISBN:
9780198526551
eISBN:
9780191723896
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198526551.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems

The connection between motoneuronal axons and skeletal muscle fibres (neuromuscular junction, NMJ) shares basic characteristics with many excitatory chemical synapses inside the central nervous ... More


Development of axons: Calcium, steering, and the growth cone

ROGER W. DAVENPORT, STEPHEN R. BOLSOVER, and S. B. KATER

in The Axon: Structure, Function and Pathophysiology

Published in print:
1995
Published Online:
May 2009
ISBN:
9780195082937
eISBN:
9780199865802
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195082937.003.0010
Subject:
Neuroscience, Disorders of the Nervous System

This chapter examines the control mechanisms underlying the establishment, modification, and repair of nervous systems as they reside at the level of the neuronal growth cone. It begins with a brief ... More


Intracellular Calcium Control Mechanisms in Glia

Maria Luisa Cotrina and Maiken Nedergaard

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0017
Subject:
Neuroscience, Development, Disorders of the Nervous System

Glial cells rely on calcium ions to display a large variety of signaling capabilities inside the cell and among neighboring cells. These calcium activities are key to regulating not only the growth ... More


Voltage-Activated Ion Channels in Glial Cells

Michelle L. Olsen and Harald W. Sontheimer

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0009
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter discusses voltage-activated ion channels in glial cells, including sodium channels, calcium channels, and potassium channels. Studies have proven that glial cells contain a large variety ... More


Spine calcium signaling

Adam Carter and Bernardo Sabatini

in Dendrites

Published in print:
2007
Published Online:
March 2012
ISBN:
9780198566564
eISBN:
9780191724206
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198566564.003.0011
Subject:
Neuroscience, Molecular and Cellular Systems

Spines are specialized cellular compartments found at high density on the dendrites of many neurons. Glutamatergic synapses are made onto spines, which house much of the local machinery necessary to ... More


Modeling Intracellular Calcium Dynamics

Erik De Schutter

in Computational Modeling Methods for Neuroscientists

Published in print:
2009
Published Online:
August 2013
ISBN:
9780262013277
eISBN:
9780262258722
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013277.003.0005
Subject:
Neuroscience, Techniques

This chapter tries to model calcium dynamics inside neurons, and analyzes the cytoplasmic calcium concentration Ci to keep the extracellular concentration Co constant. It describes how to model the ... More


Tinnitus and aging

Jos J. Eggermont

in The Neuroscience of Tinnitus

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199605606
eISBN:
9780191741555
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199605606.003.0010
Subject:
Neuroscience, Sensory and Motor Systems, Development

Tinnitus prevalence increases with age. However, a comparison between findings following noise-induced hearing loss and age-related hearing loss suggests that aging may only play a minimal role in ... More


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