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Introductory Concepts

Domitilla Del Vecchio and Richard M. Murray

in Biomolecular Feedback Systems

Published in print:
2014
Published Online:
October 2017
ISBN:
9780691161532
eISBN:
9781400850501
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691161532.003.0001
Subject:
Biology, Biochemistry / Molecular Biology

This chapter provides a brief introduction to concepts from systems biology; tools from differential equations and control theory; and approaches to the modeling, analysis, and design of biomolecular ... More


Biomolecular Feedback Systems

Domitilla Del Vecchio and Richard M. Murray

Published in print:
2014
Published Online:
October 2017
ISBN:
9780691161532
eISBN:
9781400850501
Item type:
book
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691161532.001.0001
Subject:
Biology, Biochemistry / Molecular Biology

This book provides an accessible introduction to the principles and tools for modeling, analyzing, and synthesizing biomolecular systems. It begins with modeling tools such as reaction-rate ... More


Dynamic Modeling of Core Processes

Domitilla Del Vecchio and Richard M. Murray

in Biomolecular Feedback Systems

Published in print:
2014
Published Online:
October 2017
ISBN:
9780691161532
eISBN:
9781400850501
Item type:
chapter
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691161532.003.0002
Subject:
Biology, Biochemistry / Molecular Biology

This chapter describes basic biological mechanisms in a way that can be represented by simple dynamical models. It begins with a discussion of the basic modeling formalisms that will be utilized to ... More


Application to Biomolecular Systems

Wai-yim Ching and Paul Rulis

in Electronic Structure Methods for Complex Materials: The orthogonalized linear combination of atomic orbitals

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199575800
eISBN:
9780191740992
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199575800.003.0010
Subject:
Physics, Condensed Matter Physics / Materials

Biomolecular systems are inarguably among the most complex of all known materials systems. An atomic and molecular approach is rapidly become the norm for fundamental research in the life sciences ... More


Synthetic Biology: A Systems Engineering Perspective

Domitilla Del Vecchio and Eduardo D. Sontag

in Control Theory and Systems Biology

Published in print:
2009
Published Online:
August 2013
ISBN:
9780262013345
eISBN:
9780262258906
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262013345.003.0006
Subject:
Biology, Biomathematics / Statistics and Data Analysis / Complexity Studies

This chapter presents a treatment of “retroactivity to interconnections.” It outlines some of the design challenges found in biomolecular systems from a systems engineering perspective, in ... More


Electronic Structure Methods for Complex Materials: The orthogonalized linear combination of atomic orbitals

Wai-Yim Ching and Paul Rulis

Published in print:
2012
Published Online:
September 2012
ISBN:
9780199575800
eISBN:
9780191740992
Item type:
book
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199575800.001.0001
Subject:
Physics, Condensed Matter Physics / Materials

The aim of this book is to broadly introduce a robust method for electronic structure calculation that is particularly well suited for application to large complex systems. This method, called the ... More


Molecular simulation: a virtual microscope in the toolbox of integrated structural biology

François Dehez

in From Molecules to Living Organisms: An Interplay Between Biology and Physics: Lecture Notes of the Les Houches School of Physics: Volume 102, July 2014

Published in print:
2016
Published Online:
March 2016
ISBN:
9780198752950
eISBN:
9780191814426
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198752950.003.0013
Subject:
Physics, Soft Matter / Biological Physics

Accessing the full atomistic details of complex biological processes in near physiological conditions remains challenging at the experimental level. The development of molecular modeling approaches, ... More


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