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Polysialic acid in adult brain plasticity

Abderrahman El Maarouf and Urs Rutishauser

in Neuroglycobiology: (Molecular and Cellular Neurobiology)

Published in print:
2005
Published Online:
September 2009
ISBN:
9780198525387
eISBN:
9780191723872
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198525387.003.0002
Subject:
Neuroscience, Molecular and Cellular Systems

This chapter summarizes the findings on polysialic acid function in the adult brain. In particular, the roles of polysialic acid elucidated by analysis of NCAM knockout mice are described, together ... More


Microglial Cells

Wolfgang J. Streit

in Neuroglia

Published in print:
2004
Published Online:
May 2009
ISBN:
9780195152227
eISBN:
9780199865024
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195152227.003.0005
Subject:
Neuroscience, Development, Disorders of the Nervous System

This chapter focuses on microglial cells. Microglial cell numbers are thought to make up 5% to 20% of the entire central nervous system (CNS) glial cell population. As a conservative estimate, ... More


Development of the Paraventricular Nucleus of the Hypothalamus

Larry W. Swanson

in From Development to Degeneration and Regeneration of the Nervous System

Published in print:
2008
Published Online:
May 2009
ISBN:
9780195369007
eISBN:
9780199865253
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195369007.003.0004
Subject:
Neuroscience, Molecular and Cellular Systems, Development

This chapter begins by outlining the structure-function organization of the adult paraventricular nucleus of the hypothalamus (PVH). It then reviews some highlights of what has already been learned ... More


Cerebral Plasticity: New Perspectives

Leo M. Chalupa, Nicoletta Berardi, Matteo Caleo, Lucia Galli-Resta, and Tommaso Pizzorusso (eds)

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015233
eISBN:
9780262295444
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015233.001.0001
Subject:
Neuroscience, Research and Theory

The notion that neurons in the living brain can change in response to experience—a phenomenon known as “plasticity”—has become a major conceptual issue in neuroscience research as well as a practical ... More


Plastic Reason: An Anthropology of Brain Science in Embryogenetic Terms

Tobias Rees

Published in print:
2016
Published Online:
January 2017
ISBN:
9780520288126
eISBN:
9780520963177
Item type:
book
Publisher:
University of California Press
DOI:
10.1525/california/9780520288126.001.0001
Subject:
Anthropology, Medical Anthropology

Throughout the twentieth century, neuronal researchers knew the adult human brain to be a thoroughly fixed and immutable cellular structure, devoid of any developmental potential. This book is a ... More


Nocturnal

Tobias Rees

in Plastic Reason: An Anthropology of Brain Science in Embryogenetic Terms

Published in print:
2016
Published Online:
January 2017
ISBN:
9780520288126
eISBN:
9780520963177
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520288126.003.0008
Subject:
Anthropology, Medical Anthropology

This chapter narrates the beginning of the author's research on plasticity. He spent much of his time documenting how, on the level of experimental practice, technologies were being invented that ... More


The Plastic

Tobias Rees

in Plastic Reason: An Anthropology of Brain Science in Embryogenetic Terms

Published in print:
2016
Published Online:
January 2017
ISBN:
9780520288126
eISBN:
9780520963177
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520288126.003.0015
Subject:
Anthropology, Medical Anthropology

This concluding chapter compares the work of Alain Prochiantz and Fred Gage—both of which presented the idea that some basic embryogenetic processes might continue in adult brains. While Prochiantz ... More


Letting Go

Tobias Rees

in Plastic Reason: An Anthropology of Brain Science in Embryogenetic Terms

Published in print:
2016
Published Online:
January 2017
ISBN:
9780520288126
eISBN:
9780520963177
Item type:
chapter
Publisher:
University of California Press
DOI:
10.1525/california/9780520288126.003.0014
Subject:
Anthropology, Medical Anthropology

This chapter asserts that the overarching questions that had structured the work of the lab from its inception in 1989 to 2004–2005 was: Do homeoproteins transfer between cells? Is this transfer an ... More


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