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Extraordinary Science and Psychiatry: Responses to the Crisis in Mental Health Research

Jeffrey Poland and Serife Tekin (eds)

Published in print:
2017
Published Online:
September 2017
ISBN:
9780262035484
eISBN:
9780262341752
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035484.001.0001
Subject:
Psychology, Clinical Psychology

The subject of the book is the culture of crisis and controversy that exists in contemporary mental health research, following the publication of the fifth edition of the Diagnostic and Statistical ... More


Introduction: Psychiatric Research and Extraordinary Science

Jeffrey Poland and Şerife Tekin (eds)

in Extraordinary Science and Psychiatry: Responses to the Crisis in Mental Health Research

Published in print:
2017
Published Online:
September 2017
ISBN:
9780262035484
eISBN:
9780262341752
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035484.003.0001
Subject:
Psychology, Clinical Psychology

This chapter introduces the core thematic ideas of the present volume: that psychiatric research is in crisis, that it has entered a period of extraordinary science, and that a fully adequate ... More


Evidence-Based Medicine, Biological Psychiatry, and the Role of Science in Medicine

Robyn Bluhm

in Extraordinary Science and Psychiatry: Responses to the Crisis in Mental Health Research

Published in print:
2017
Published Online:
September 2017
ISBN:
9780262035484
eISBN:
9780262341752
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035484.003.0003
Subject:
Psychology, Clinical Psychology

Both evidence-based medicine (EBM) and biological psychiatry aim to improve clinical practice by basing it more firmly on the results of scientific research. In this chapter, however, I show that ... More


RDoC’s Metaphysical Assumptions: Problems and Promises

Ginger A. Hoffman and Peter Zachar

in Extraordinary Science and Psychiatry: Responses to the Crisis in Mental Health Research

Published in print:
2017
Published Online:
September 2017
ISBN:
9780262035484
eISBN:
9780262341752
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035484.003.0004
Subject:
Psychology, Clinical Psychology

Critics contend that the categories within the DSM are fueling the current crisis in psychiatry because they are not valid. As a remedy, NIMH has established RDoC, a framework of psychological and ... More


Pathophysiological Toolkit: Genes to Circuits

Gül Dölen, Robert C. Malenka, Joel S. Perlmutter, Nils Brose, Richard Frackowiak, Bruce N. Cuthbert, Ilka Diester, Isabelle Mansuy, Katja S. Kroker, Tobias M. Boeckers, Alvaro Pascual-Leone, and Guoping Feng

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0010
Subject:
Neuroscience, Research and Theory

Understanding the etiology and pathophysiology of neuropsychiatric disease requires the development of new tools (ranging from evolving diagnostic strategies to biomarkers) that can address the ... More


Psychotic Disorders and the Neurodevelopmental Continuum

Michael J. Owen

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0003
Subject:
Neuroscience, Research and Theory

This chapter considers adult psychiatric disorders (schizophrenia and bipolar disorder) and childhood neurodevelopmental disorders (autism spectrum disorder and intellectual disability). The primary ... More


Neurodevelopmental Disorders: What Is to Be Done?

Stephan Heckers, Steven E. Hyman, Thomas Bourgeron, Bruce N. Cuthbert, Raquel E. Gur, Cynthia Joyce, Andreas Meyer-Lindenberg, Michael J. Owen, and Matthew W. State

in Translational Neuroscience: Toward New Therapies

Published in print:
2015
Published Online:
September 2016
ISBN:
9780262029865
eISBN:
9780262329859
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262029865.003.0004
Subject:
Neuroscience, Research and Theory

Autism and schizophrenia are associated with abnormalities in brain development, the genetic and environmental risk factors of which are just now being discovered. How can these advances be ... More


Current State of Psychiatric Nosology

Michael B. First

in Computational Psychiatry: New Perspectives on Mental Illness

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262035422
eISBN:
9780262337854
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035422.003.0008
Subject:
Psychology, Cognitive Neuroscience

Psychiatric classifications categorize how patients present to mental health care professionals and are necessarily utilitarian. From the clinician’s perspective, the most important goal of a ... More


Clinical Heterogeneity Arising from Categorical and Dimensional Features of the Neurobiology of Psychiatric Diagnoses: Insights from Neuroimaging and Computational Neuroscience

John H. Krystal, Alan Anticevic, John D. Murray, David Glahn, Naomi Driesen, Genevieve Yang, and Xiao-Jing Wang

in Computational Psychiatry: New Perspectives on Mental Illness

Published in print:
2016
Published Online:
May 2017
ISBN:
9780262035422
eISBN:
9780262337854
Item type:
chapter
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262035422.003.0016
Subject:
Psychology, Cognitive Neuroscience

Clinical heterogeneity presents important challenges to optimizing psychiatric diagnoses and treatments. Patients clustered within current diagnostic schema vary widely on many features of their ... More


Psychiatric nosology and cognitive enhancement

Dan J. Stein

in Rethinking Cognitive Enhancement

Published in print:
2017
Published Online:
April 2017
ISBN:
9780198727392
eISBN:
9780191835230
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198727392.003.0014
Subject:
Psychology, Psychopharmacology, Cognitive Neuroscience

There has been renewed interest in psychiatric classification, with the recent development of the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), the 11th edition of ... More


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