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Genome structure and function

Jan Vijg

in Aging of the Genome: The dual role of DNA in life and death

Published in print:
2007
Published Online:
April 2010
ISBN:
9780198569237
eISBN:
9780191728242
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198569237.003.0003
Subject:
Biology, Evolutionary Biology / Genetics

This chapter focuses on those components of genome structure that have the potential to drive its demise in somatic cells over time, based on current knowledge of the sources of somatic damage in ... More


Darwinian Reductionism: Or, How to Stop Worrying and Love Molecular Biology

Alexander Rosenberg

Published in print:
2006
Published Online:
March 2013
ISBN:
9780226727295
eISBN:
9780226727318
Item type:
book
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226727318.001.0001
Subject:
Philosophy, Philosophy of Science

After the discovery of the structure of DNA in 1953, scientists working in molecular biology embraced reductionism—the theory that all complex systems can be understood in terms of their components. ... More


Reframing Rights: Bioconstitutionalism in the Genetic Age

Sheila Jasanoff (ed.)

Published in print:
2011
Published Online:
August 2013
ISBN:
9780262015950
eISBN:
9780262298667
Item type:
book
Publisher:
The MIT Press
DOI:
10.7551/mitpress/9780262015950.001.0001
Subject:
Biology, Bioethics

Legal texts have been with us since the dawn of human history. Beginning in 1953, life too became textual. The discovery of the structure of DNA made it possible to represent the basic matter of life ... More


“It Almost Came Out on Its Own”: Nature under L. J. F. Brimble and A.J.V. Gale

Melinda Baldwin

in Making "Nature": The History of a Scientific Journal

Published in print:
2015
Published Online:
January 2016
ISBN:
9780226261454
eISBN:
9780226261591
Item type:
chapter
Publisher:
University of Chicago Press
DOI:
10.7208/chicago/9780226261591.003.0006
Subject:
History, History of Science, Technology, and Medicine

This chapter discusses two of Nature’s less prominent editors: Richard Gregory’s former assistants L.J.F. Brimble and A.J.V. Gale. Brimble and Gale led Nature through the difficult wartime years and ... More


X-ray diffraction of polycrystalline materials

Christopher Hammond

in The Basics of Crystallography and Diffraction

Published in print:
2015
Published Online:
August 2015
ISBN:
9780198738671
eISBN:
9780191801938
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780198738671.003.0010
Subject:
Physics, Crystallography, Condensed Matter Physics / Materials

Chapter 10 begins by considering the geometrical basis of polycrystalline (powder) X-ray diffraction techniques, i.e. the focusing circle, focusing, and semi-focusing methods. It then considers the ... More


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