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The Alzheimer Conundrum: Entanglements of Dementia and Aging

Margaret Lock

Published in print:
2013
Published Online:
October 2017
ISBN:
9780691149783
eISBN:
9781400848461
Item type:
book
Publisher:
Princeton University Press
DOI:
10.23943/princeton/9780691149783.001.0001
Subject:
Anthropology, Social and Cultural Anthropology

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no ... More


Iris on Safari: A Personal Record

John Bayley

in Iris Murdoch, Philosopher

Published in print:
2011
Published Online:
September 2012
ISBN:
9780199289905
eISBN:
9780191728471
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780199289905.003.0003
Subject:
Philosophy, History of Philosophy, Moral Philosophy

This chapter presents a short memoir of Iris Murdoch as lecturer and traveller—and her relations, among other things, to God, to power (and Elias Canetti), and to what Philippa Foot has called ... More


Memories, Magic, & a Major Addiction

Gary L. Wenk

in Your Brain on Food: How Chemicals Control Your Thoughts and Feelings

Published in print:
2010
Published Online:
September 2010
ISBN:
9780195388541
eISBN:
9780199863587
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195388541.003.0002
Subject:
Neuroscience, Behavioral Neuroscience, Neuroendocrine and Autonomic

The actions of the neurotransmitter acetylcholine influence the function of many brain regions. Within these regions, acetylcholine allows you to learn and remember, to regulate your attention and ... More


Brain Enhancement and Other Magical Beliefs

Gary L. Wenk

in Your Brain on Food: How Chemicals Control Your Thoughts and Feelings

Published in print:
2010
Published Online:
September 2010
ISBN:
9780195388541
eISBN:
9780199863587
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195388541.003.0009
Subject:
Neuroscience, Behavioral Neuroscience, Neuroendocrine and Autonomic

No drugs or nutrients are currently available that can reverse the primary cause of cognitive decline: normal aging. Also, it is currently impossible to enhance the function of a normal brain. These ... More


The Early Detection of Alzheimer's Disease with Positron Emission Tomography

Rachel Mistur, Lisa Mosconi, Remigiusz Switalski, Susan De Santi, Yi Li, Lidia Glodzik, Miroslaw Brys, Wai Tsui, Henry Rusinek, and Mony J. de Leon

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0011
Subject:
Neuroscience, Techniques, Development

Reductions in the cerebral metabolic rate of glucose (CMRglc), a measure of neuronal function, have proven to be a promising tool in the early diagnosis of Alzheimer's disease (AD). FDG-PET imaging ... More


Differential Diagnosis of Dementia Using Functional Neuroimaging

Eric Salmon, Fabienne Collette, and Gaëtan Garraux

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0015
Subject:
Neuroscience, Techniques, Development

Functional neuroimaging in neurodegenerative dementias provides 3D representations of brain activity that are relatively characteristic of the underlying phenotypic distribution of cerebral lesions. ... More


MRI and the Differential Diagnosis of Dementia

António J. Bastos-Leite and Philip Scheltens

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0016
Subject:
Neuroscience, Techniques, Development

Magnetic resonance imaging (MRI) has opened up the way to diagnose dementia in vivo. It provides clear evidence for hippocampal atrophy in Alzheimer's disease (AD), lobar atrophy in frontotemporal ... More


White Matter Hyperintensities in Aging and Dementia

Adriane Mayda, Mitsuhiro Yoshita, and Charles DeCarli

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0017
Subject:
Neuroscience, Techniques, Development

Both advancing age and cognitive impairment are associated with increased prevalence of various brain diseases, with Alzheimer's disease (AD) and cerebrovascular disease (CVD) being the most common. ... More


MRI as a Surrogate Marker in Clinical Trials in Alzheimer’s Disease

Frank Jessen and Harald Hampel

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0019
Subject:
Neuroscience, Techniques, Development

The rapid development of novel treatment targets for Alzheimer's disease (AD) requires tools to assess the effects of these treatments on disease progression. Structural neuroimaging with CCT and ... More


Databasing the Aging Brain

John Darrell, Van Horn, and Arthur W. Toga

in Imaging the Aging Brain

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195328875
eISBN:
9780199864836
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195328875.003.0021
Subject:
Neuroscience, Techniques, Development

Large-scale archives of primary neuroimaging data of older populations are an essential element for contemporary research into normal and disease processes associated with aging. In this chapter, we ... More


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