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Neurochemical Modulation of Prefrontal Cortical Function in Humans and Animals

Amy F.T. Arnsten and Trevor W. Robbins

in Principles of Frontal Lobe Function

Published in print:
2002
Published Online:
May 2009
ISBN:
9780195134971
eISBN:
9780199864157
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195134971.003.0004
Subject:
Neuroscience, Behavioral Neuroscience, Molecular and Cellular Systems

The cognitive functions of the prefrontal cortex (PFC), which include use of working memory to guide behavioral responses and the contents of attentional focus, the inhibition of inappropriate ... More


Genetic Dissection of Dopamine-Mediated Prefrontal-Striatal Mechanisms and Its Relationship to Schizophrenia

Hao-Yang Tan and Daniel R. Weinberger

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0013
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter examines findings through which heritable human neuroimaging intermediate phenotypes could provide a window to examine genetic mechanisms of active prefrontal cognitive processing ... More


Dopamine’s Influence on Prefrontal Cortical Cognition: Actions and Circuits in Behaving Primates

Amy F.T. Arnsten, Susheel Vijayraghavan, Min Wang, Nao J. Gamo, and Constantinos D. Paspalas

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0016
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter summarizes current knowledge of dopamine (DA) and DA receptor localization in primate prefrontal cortex (PFC), and the powerful influences of DA on PFC physiology and cognitive function. ... More


Neurocomputational Analysis of Dopamine Function

Daniel Durstewitz

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0018
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

Current computational models of dopamine (DA) modulation have worked either from a more abstract neuroalgorithmic level, starting with specific assumptions about DA's computational role and then ... More


Contributions of Mesocorticolimbic Dopamine to Cognition and Executive Function

Stan B. Floresco

in Dopamine Handbook

Published in print:
2009
Published Online:
February 2010
ISBN:
9780195373035
eISBN:
9780199865543
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195373035.003.0015
Subject:
Neuroscience, Molecular and Cellular Systems, History of Neuroscience

This chapter presents a summary of studies that have investigated the contribution of prefrontal cortex (PFC) dopamine (DA) transmission to higher-order cognition, and compares and contrasts the ... More


Sex Differences in Cognitive Function in Rodents

Victoria Luine and Gary Dohanich

in Sex Differences in the Brain: From Genes to Behavior

Published in print:
2007
Published Online:
January 2010
ISBN:
9780195311587
eISBN:
9780199865048
Item type:
chapter
Publisher:
Oxford University Press
DOI:
10.1093/acprof:oso/9780195311587.003.0012
Subject:
Neuroscience, Molecular and Cellular Systems

Qualitative sexual dimorphisms in cognition and behavior may afford each sex with the requisite tools that provide an edge for their mutual survival and for the survival of their progeny. This ... More


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